The strong and the fast: cooperation among intracellular Salmonella

Speaker: Dr. Ondrej Cerny, Czech Academy of Sciences in Prague

Talk:  The strong and the fast: cooperation among intracellular Salmonella

Time: 04.04.2025, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B

Dr. Ondrej Cerny studies interaction of pathogenic bacteria with their host at single cell level. He currently works at the Institute of Microbiology of the Czech Academy of Sciences in Prague, the Czech Republic. After his PhD, he started working on effector proteins involved in Salmonella intracellular live style in the lab of David Holden at Imperial College London, the United Kingdom. He studied Salmonella interaction with dendritic cells and the influence of the effector protein SteD on cell surface major histocompatibility complex class II (MHCII) and immunological synapse between infected dendritic cells and T cells. He identified the immunological synapse and its destabilization as a target for pathogenic bacteria allowing them to influence diverse T cell subsets. He moved back to the Institute of Microbiology of the Czech Academy of Sciences in 2021. Since 2025, he heads his own laboratory focusing on intracellular lifestyles of Salmonella. In his seminar, he will focus on cooperative virulence among distinct subpopulations of intracellular Salmonella.