Invited speakers

A molecular switch to adjust activity and specificity of the quality control ubiquitin ligase CHIP

Speaker:  dr Wojciech Pokrzywa, Laboratory of Protein Metabolism at the International Institute of Molecular and Cell Biology in Warsaw

Talk:  A molecular switch to adjust activity and specificity of the quality control ubiquitin ligase CHIP

Time:  25.11.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B


BSDr hab. Wojciech Pokrzywa is a molecular biologist heading the Laboratory of Protein Metabolism at the International Institute of Molecular and Cell Biology in Warsaw. His research focuses on the ubiquitin-proteasome system, chaperone network, regulation of translation, and muscular exophers in proteostasis. His laboratory uses a combination of biochemical, microscopic, molecular genetics, and bioinformatics techniques, supported by mammalian cell assays and the nematode Caenorhabditis elegans.

Wojciech received his first M.Sc. degree in Microbiology at the University of Wroclaw, Poland. Next, he moved to Belgium, where he obtained his second M.Sc. degree and his Ph.D. in Biological Engineering and Agronomic Sciences at the Catholic University of Louvain. He did his postdoctoral fellowship at the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Germany, in the group of prof. Thorsten Hoppe, during which he published in, i.a., Cell, Cell Metabolism, Nature Communications, or Nature Structural & Molecular biology. Since 2017 he runs his own interdisciplinary research group at the International Institute of Molecular and Cell Biology in Warsaw and has already published several articles in journals such as EMBO Journal, EMBO reports, Molecular Cell, and Nature Communications.

Wojciech is an awardee of multiple national and European grants, many of which are for highly collaborative projects with Polish and international groups. He received OPUS, GRIEG, and SONATA BIS from the National Science Centre (Poland), FIRST TEAM from the Foundation for Polish Science, EMBO Installation Grant, and funding from the German Research Foundation (DFG) for the consortium project on mechanical stress protection. Wojciech is also a keen science popularizer – apart from conducting the lectures at the Festival of Science in Warsaw, he recently received a Social Responsibility of Science grant from the Ministry of Education and Science for developing an educational computer game about the mechanisms of protein degradation. In addition, Wojciech is also a successful mentor of early career researchers, as his Ph.D. students receive prestigious awards, including the PRELUDIUM grants from the National Science Centre (Poland) or Fulbright Junior Research Award. .

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Data publikacji: poniedziałek, 14. Listopad 2022 - 07:51; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 14. Listopad 2022 - 07:59; osoba wprowadzająca: Maria Maja Pega

Mitochondrial DNA: bystander or active contributor to inflammation?

Speaker:  prof. Bartosz Szczesny, University of Texas Medical Branch, Galveston, USA

Talk:  "Mitochondrial DNA: bystander or active contributor to inflammation?"

Time:  18.11.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B


BSBartosz Szczesny, PhD is an associate professor in the Departments of Ophthalmology and Visual Sciences, and Anesthesiology at the University of Texas Medical Branch (UTMB) at Galveston, Texas. He completed his MSc and PhD at the University of Wroclaw, Poland, and postdoctoral training at UTMB. The focus of his research group is to understand the role of mitochondrial dysfunction, particularly mitochondrial DNA damage and repair, in physiological and pathological conditions. He will be discussing the dual role of mitochondrial DNA that is actively released from injured cells via extracellular vesicles as an important signaling molecule in the induction of inflammatory response, and as a novel marker of cell injury. He will present recent advances in understanding the novel role of damaged mitochondrial DNA derived from epithelial cells in activation of microglia in the central nervous system/retina and alveolar macrophages in lungs. He will also present recently developed and validated method for fast, inexpensive, and accurate measurement of cell free DNA as a liquid biopsy technology for the early detection and quantitative monitoring of trauma severity. He will be discussing the presence of cell/organ specific markers within circulating extracellular vesicles containing DNA as a novel biomarker for the assessment of traumatic brain injury. His research is supported by NIH, NSF, and private foundations.

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Data publikacji: poniedziałek, 31. Październik 2022 - 17:41; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 31. Październik 2022 - 17:47; osoba wprowadzająca: Maria Maja Pega

Applications of Genetic and Genomic Technologies in Animal Production

Speaker:  dr Andrzej Sosnicki, Global Technical Projects, US

Talk:  "Applications of Genetic and Genomic Technologies in Animal Production"

Time:  28.10.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B


dr SosnickiAndrzej Sosnicki received his MS in Biology/Animal Physiology and Ph.D. in Agricultural Sciences/Muscle Biology from the University of Life Sciences in Poznan, Poland. As an Assistant and then Associate Professor he was conducting skeletal muscle physiology and pathology research, and he taught undergraduate and graduate courses at the Department of Zootechnical Sciences.

In 1985 Andrzej relocated to the Muscle Biology & Meat Science Laboratory, University of Wisconsin-Madison where he studied muscle histopathology and meat quality of poultry and red-meat animals. Subsequently, in 1988 he moved to the Department of Zoology, University of Tennessee, Knoxville, where he researched skeletal muscle physiology & locomotion. In 1989 Andrzej  joined the Department of Biology at the University of Pennsylvania, Philadelphia, where he further focused on studying physiological principles of skeletal muscle function during locomotion.

In 1990 Dr. Sosnicki relocated back to Madison, WI where he worked at the R&D Department of Oscar Mayer Foods Corporation (OMFC)/Kraft Foods Corp. At OMFC he was a Manager of the Animal & Poultry Research division directing integrative research focusing on creating value in vertically integrated poultry & pork production and meat processing systems.

In 1995 joined PIC to establish and manage the company’s Muscle Biology Program, emphasizing the commercial importance of pig carcass value in Pig Improvement Company (PIG) genetic improvement program. During his tenure at PIC, he has also developed and managed PIC’s Performance Validation Program, and he has been Director of Genus-PIC Global Technical Services. He has also been responsible for P&L of business accounts in North and Latin America and in the EU. Dr. Sosnicki is currently Director of Global Technical Projects further integrating pig growth and skeletal muscle physiology into the matrix of PIC’s genetic improvement program.

Dr. Sosnicki is the author/co-author of over forty publications, six book chapters and several popular-science articles. He was an Adjunct Associate Professor at the Department of Animal Science of Iowa State University, Ames, IA in 2002-2010, and an Adjunct Associate Professor at the Department of Animal & Avian Sciences of the University of Maryland, College Park, MD in 2016-2019. He is a reviewer of American Meats Science Association’s ‘Myth Crusher’, Meat Science, Livestock Sciences (also a member of the Editorial Committee), and Journal of Animal Science scientific magazines. He received American Meat Institute Distinguished Extension-Industry Service Award in 2013 and American Meat Science Association’s International Lectureship Award in 2015.

 

The title of the Seminar “Applications of Genetic and Genomic Technologies in Animal Production” clearly implies that the seminar will primarily focus on the practical aspects of Animal Breeding & Production, although the information will not be all inclusive due to limited time availability. We will discuss the value of animal genetic and genomics tools, computation technology, elite farms housing pure lines, commercial lines, and cross-bred pedigreed populations as the foundation of the best possible rates of genetic improvement.

Today, the global production-to-consumption animal-source food systems are complex, and  meats now are safer, tastier, more nutritious, abundant, diverse, and convenient, and less costly than ever before. Future advancements in genetic and genomic selection will enable implementation of more complex and successful breeding programs further contributing to the success of the modern, sustainable pork production.

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Data publikacji: wtorek, 11. Październik 2022 - 08:17; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 31. Październik 2022 - 17:48; osoba wprowadzająca: Maria Maja Pega

Genetic mechanisms in atopic eczema – from population to cell biology

Speaker:  prof. Sara Brown, The University of Edinburgh, UK

Talk:  "Genetic mechanisms in atopic eczema – from population to cell biology"

Time:  21.10.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B


Sara BrownProfessor Sara Brown is a clinical academic, with research focused on genetic predisposition to the inflammatory skin disease atopic/eczema and associated systemic conditions. She graduated with Honours in Medicine & Surgery from the University of Edinburgh and completed her specialist training in Dermatology in Newcastle-upon-Tyne and then obtained an MD in Human Genetics with commendation in 2008. She spent 10 months as a post-CCT Fellow in Paediatric Dermatology in Dublin, Ireland, before moving to Dundee in October 2009.

Sara was awarded a Wellcome Trust Intermediate Clinical Fellowship in 2009, to continue her research on the role of filaggrin in atopic disease. In 2014 Sara established her own lab in the School of Medicine and in 2015 was the first UK dermatologist to be awarded a prestigious Wellcome Trust Senior Research Fellowship in Clinical Science, in recognition and support of her on-going research in molecular genetic dermatology focussed on understanding eczema pathogenesis. In 2015 Sara was promoted to a Personal chair in Molecular and Genetic Dermatology. Her lab moved to the Institute of Genetics and Cancer, University of Edinburgh in 2020.

Sara become interested in genetic mechanisms underlying skin disease at the time of the ground-breaking discovery of FLG mutations. She conducted the first population-based cohort study to show that FLG null mutations affect risk of the milder eczema phenotype that is very prevalent in the community, in addition to the severe disease. Sara continued her research in atopic eczema and she has developed a pipeline of discovery from genomic and genetic variation at the population level, to subgroups in vivo and mechanistic studies in vitro. She is an active member of a European Barrier Epidermal Research Network (E2BRN) and was recently elected its co-chair; she also takes part in Europe-wide COST initiatives related to the skin. As a clinician-scientist Sara has participated in multiple research trials and multi-centre studies focused on eczema genetics. Her contributions include multiple publications in high-end journals, incl. J Allergy Clin Immunol, Lancet, J Investigative Dermatology, Nature Genetics, Nature Communications, PLOS One Medicine, J Am Acad Dermatology.

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Data publikacji: środa, 5. Październik 2022 - 10:22; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 19. Październik 2022 - 08:15; osoba wprowadzająca: Maria Maja Pega

Allele differences in the sRNA arcZ gene result in variant prokaryotic and eukaryotic antimicrobial activities of Dickeya solani against bacteria, yeast and fungi.

Speakerdr Erwan Gueguen, University of Lyon, Laboratory MAP CNRS UMR5240

Talk:  "Allele differences in the sRNA arcZ gene result in variant prokaryotic and eukaryotic antimicrobial activities of Dickeya solani against bacteria, yeast and fungi."

Time:  14.10.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Erwan GueguenAbstract:

The necrotrophic plant pathogenic bacterium Dickeya solani is an invader of the potato agrosystem in Europe. All isolated strains of D. solani contain several large polyketide/fatty acid/non-ribosomal peptide synthetase clusters. Analogy with genes described in other bacteria suggests that two clusters are involved in the production of secondary metabolites of the oocydin and zeamine families. A 3rd cluster that we named ssm for Solani secondary metabolite had an unknown function. In this study, we used a reverse genetics strategy to create mutants impacted in the three secondary metabolite clusters ssm, ooc, and zms to compare the phenotype of the D. solani strain D s0432-1 with its associated mutants. We demonstrated the antimicrobial functions of these three PKS/NRPS clusters against, yeasts and fungi of the phylum Ascomycota. We unveiled the function of the new secondary metabolite cluster ssm (for solani secondary metabolite), only conserved in some Dickeya species, which produces a secondary metabolite inhibiting yeasts. Finally, phenotyping and small-scale comparative genomic of WT isogenic D. solani strains led us to the discovery that the sRNA ArcZ plays a primary role in the control of the three PKS/NRPS clusters ssm, ooc and zms. 

CV of Erwan Gueguen: 

Erwan Gueguen received his PhD in molecular microbiology from Paul Sabatier University in 2006, where he explored the transposition mechanism of the mobile genetic element IS911. He completed his postdoctoral training in two distinct labs. From 2007 to 2010, he worked in Andrew Darwin's laboratory at New York University, where he studied the Psp stress response system of Yersinia enterocolitica, and from 2010 to 2012, he worked in Eric Cascales' lab at CNRS in Marseille, France, where he studied the type 6 secretion systems of bacteria in the genus Yersinia and Citrobacter. In 2012, he was hired as a permanent researcher and lecturer at the University of Lyon (France) to investigate first the resistance of bacteria to heavy metals and then the mechanism of plant infection by bacteria of the genus Dickeya. Erwan Gueguen is a bacterial genetics expert. He recently developed the high-throughput transposon sequencing approach for the bacterium Dickeya dandatii and cooperated on its application in D. solani and Xanthomonas hortorum. He recently became interested in the bacterium Dickeya solani, a very aggressive pathogen of potato agrosystem. Dr Gueguen is also very involved in teaching. He is the head of the microbial genetics teaching team and the head of the microbiology program for the life sciences degree at the Claude Bernard University in Lyon.

 

A short presentation of Typhaine Brual, a PhD student of Dr. Erwan Gueguen will follow the talk of Dr. Gueguen

 

Typhaine BrualAbstract:

Regulation of the virulence of pectinolytic bacteria by RsmC protein

Pectinolytic bacteria are responsible for soft rot disease in plants. At the beginning of the infection, these bacteria multiply while evading the plant's immune system. When they are in sufficient numbers, they produce enzymes such as pectinases to digest the plant cell wall[1]. The timing of the onset of pectinases secretion is decisive and is finely regulated: if it occurs too early, the infection is not efficient. Motility is also crucial for host colonization an immobile mutant does not cause symptoms. The flagellum is also a target of the plant immune system, so its synthesis is highly controlled. Deciphering these regulatory mechanisms is important for understanding the development of virulence in these bacteria. A previous work from my laboratory showed that a protein named RsmC would play a role in the control of virulence in Dickeya dadantii, a model organism of pectinolytic bacteria[2]. The rsmC gene is conserved only in Pectobacteriaceae and has been poorly studied.The structure of RsmC is unknown and only one study describes this protein as an "anti-FlhDC protein", i.e. a repressor of the FlhDC regulator, a complex regulating both motility and secretion of pectinases[3].

The objective of my work is to understand the role of RsmC in the regulation of virulence in D. dadantii using two approaches: 1) Defining the interactome of RsmC, to understand by which intermediary this protein exerts its function; 2) Deciphering the expression conditions of the rsmC gene to study when and how RsmC intervenes in the life cycle of D. dadantii.

[1] Hugouvieux-Cotte-Pattat N. et al., 2020. eLS John Wiley & Sons, Ltd : Chichester

[2] Royet K. et al., 2019. Molecular Plant Pathology, 20,287-306.

[3] Chatterjee A. et al., 2009. Journal of Bacteriology, 191, 4582-4593.

 

 

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Data publikacji: czwartek, 29. Wrzesień 2022 - 12:39; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 5. Październik 2022 - 10:31; osoba wprowadzająca: Maria Maja Pega

Modelling of SARS-CoV-2 infection as a tool to reveal new viral mechanisms

Speaker:  dr Tomasz Turowski, IBB PAN, Warszawa

Talk:  "Modelling of SARS-CoV-2 infection as a tool to reveal new viral mechanisms"

Time:  10.06.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


dr Tomasz Turowski, IBB PAN, Warszawa

Dr. Tomasz Turowski holds a Master Degree in Molecular Biology (from Nicolaus Copernicus University in Torun). In 2013 he was awarded his PhD in Chemistry at the Warsaw University of Technology (Institute of Biotechnology), working on coupling between tRNA transcription and decay under the supervision of Prof. Magdalena Rakowska-Boguta. He carried out his postdoctoral training at the Wellcome Centre for Cell Biology at the University of Edinburgh (Scotland, UK) in the group of Prof. David Tollervey. During this time, he got interested in biochemistry and bioinformatics.  Tomasz’s research interests include transcription elongation of RNA polymerase I and III, which are relatively unique transcription systems in higher organisms. During the SARS-CoV-2 pandemic he participated in a collaborative effort to characterize SARS-CoV-2 host-virus interactions during viral infection. His recent work combines an interdisciplinary approach utilising UV cross-linking in vivo, bioinformatics and mathematical modelling. Tomasz was awarded a Polish Return grant funded by NAWA and in August 2021 started his own group at the Institute of Biochemistry and Biophysics Polish Academy of Sciences in Warsaw. The Laboratory of Transcription Mechanisms headed by Dr. Turowski is interested in understanding how the transcription affects gene regulation. They apply basic knowledge to problems such as SARS-CoV-2 transcription and RNA polymerase III-related leukodystrophy.

 

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Data publikacji: wtorek, 31. Maj 2022 - 08:37; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 31. Maj 2022 - 08:42; osoba wprowadzająca: Maria Maja Pega

Functional Lipid liquid-liquid immiscibility at immune interfacial barriers

Speakerdr Jorge Bernardino De La Serna, Faculty of Medicine, National Heart & Lung Institute, Imperial College London

Talk:  "Functional Lipid liquid-liquid immiscibility at immune interfacial barriers"

Time:  27.05.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


DR JORGE BERNARDINO DE LA SERNA

Dr Bernardino de la Serna holds two Master Degrees, one in Chemistry and another in Biochemistry (from University Complutense of Madrid (Spain). He was awarded his PhD at the working in the Department of Biochemistry and Molecular Biology under the supervision of Prof. Perez-Gil. 

He carried out his postdoctoral training at the Center for BioMembrane Physics (MEMPHYS) at the University of Southern Denmark. In 2014 Jorge was awarded Marie Skłodowska-Curie Career Integration Fellowship and moved to the University of Oxford (United Kingdom). There he was based at the MRC-Weatherall Institute of Molecular Medicine, Nuffield Department of Medicine, in the group of Prof. Christian Eggeling. During this time he got interested in super resolution imaging and undertook additional training in super-resolution fluorescence microscopy at the lab of Nobel Prize Laureate Prof. Stephan Hell at the Max Planck Institute for Biophysical Chemistry, Göttingen (Germany). Thereafter, he moved to the Oxford-Harwell Campus to undertake a new role of a Staff Scientist at the United Kingdom Research and Innovation (UKRI), working at the Central Laser Facility at the Rutherford Appleton Laboratory. In 2019 Jorge joined the National Heart and Lung Institute, Imperial College London (United Kingdom) as a Senior Lecturer. His academic career also includes additional research stays, e.g. fellowship at the Humboldt University in Berlin and stays at the University of California at Santa Barbara, Venezuelan Institute for Scientific Investigations (IVIC) in Caracas Venezuela, SENAI/CETIQT in Rio de Janeiro, Brazila and Umeå University in Sweden.

Jorge’s interests include research on molecular sensing and remodeling in the airways,  interactions between host cell and toxic pollutants, nanoparticles and pathogens, engineered nanoparticles as drug delivery systems, organ-on-a-chip models and advanced imaging techniques, incl. super-resolution (STED) fluorescence microscopy.

 

 

 

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Data publikacji: wtorek, 24. Maj 2022 - 07:57; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 24. Maj 2022 - 07:57; osoba wprowadzająca: Maria Maja Pega

Immune modulatory extracellular vesicles: applications as biomarkers and for clinical treatment

Speakerprof. Susanne Gabrielsson, Karolinska Institutet, Department of Medicine Clinical Allergy Research Unit, Solna, Sweden

Talk:  "Immune modulatory extracellular vesicles: applications as biomarkers and for clinical treatment"

Time:  06.05.2022, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


WS

Prof. Gabrielsson graduated with a PhD from Stockholm University. She then moved to France for as a postdoc at the Curie Institute in Paris, developing interest in dendritic cells and T cell responses. After this, she returned to Sweden and  established a group dedicated to exosome research at the Karolinska Institutet. Susanne has been a pioneer in the field of immune effects of exosomes and she is one of the leading authors of the field having published 37 articles on the subject.

She was the first to describe the presence of exosomes in bronchoalveolar lavage fluid, as well as in breast milk. Her work has revealed that exosomes are major players in lung diseases such as asthma and sarcoidosis, where they contribute to inflammation. Professor Gabriellson lab carries out  studies in animal models to give new insights into the role of exosomes in cancer progression. She also has a major interest in exosome-based therapies for immunotherapeutic applications or biomarkers in cancer.

 

 

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Data publikacji: czwartek, 28. Kwiecień 2022 - 06:53; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 29. Kwiecień 2022 - 08:50; osoba wprowadzająca: Maria Maja Pega

Modeling protein-glycosaminoglycan interactions in biologically relevant systems

Speaker: Sergey Samsonov

Talk:  "Modeling protein-glycosaminoglycan interactions in biologically relevant systems"

Time:  08.04.2022, 9:00 am

Venue:  Online and Live in the "IFB seminars" group of MS Teams. Group password: ypidr3d


 

.Sergey Samsonov graduated in Biophysics at Peter the Great St. Petersburg Polytechnic University in 2006. He obtained his first PhD in 2009 in Bioinformatics at the Dresden University of Technology, where he investigated the impact of solvent and effects of fluorination in protein-protein interactions. In 2010 he obtained his second PhD title in the field of Biochemistry at St. Petersburg University for the continuation of his Master Thesis topic on copper metabolism proteins. Since then and until 2017 he was a postdoctoral researcher in the group of Structural Bioinformatics at Dresden University of Technology within the project “Transregio 67: Functional biomaterials for controlling healing processes in bone and skin tissue – from material to clinic”, where he started to work in the field of modelling glycosaminoglycans (GAG) containing biomolecular systems. In 2017 he received a joint grant from National Centre of Sciences (Poland) and EU Commission within POLONEZ Programme to start his own research group at the University of Gdańsk. In 2018 he obtained the title of dr hab. at the University of Tours (France) (Habilitation à diriger des recherches). In 2019, he received two new grants from National Centre of Sciences (Poland), one of which is within collaborative Programme with German Research Council, both of which represent the extension of his GAG modeling studies. His research interests are in approaching the understanding of various aspects of GAG interactions with other biomacromolecules and development of specific methodology for this class of polysaccharides with the assistance of molecular docking, molecular dynamics, free energy calculations and quantum chemistry approaches.

 

 

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Data publikacji: poniedziałek, 4. Kwiecień 2022 - 13:05; osoba wprowadzająca: Monika Sączewska Ostatnia zmiana: czwartek, 28. Kwiecień 2022 - 06:45; osoba wprowadzająca: Monika Sączewska

Symsagittifera roscoffensis as a main Actor* of The Plant~Animals ~ Symbiosity of Creation

Speaker Elvin Flamingo and Xavier Bailly

Talk:  "Symsagittifera roscoffensis as a main Actor* of The Plant~Animals ~ Symbiosity of Creation"

Time:  11.03.2022, 9:00 am

Venue:  Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d


Elvin Flamingo and Xavier BaillyElvin Flamingo is an artist working in the fields of Bioart and Art&Science. His projects combine art, biology, and technology. His most important project, thus far, is The Symbiosity of Creation, which was the topic of his doctoral thesis. It began in 2012 and is planned to continue to 2034. The work's point of departure is the cultivation of exotic ants. It consists of three parts invoking the themes of destruction and re-creation. The Symbiosity of Creaton received broad national and international coverage and was presented at various exhibitions, including Kunsthal Aarhus in Denmark, at the Art&Science Convesations seminar in Kassel, Germany, and at TEDx Between Genres exhibition in Gdynia. It received the Critic's Award at the Media Art Biennale WRO: Test Exposure, Wrocław, Poland, in 2015.

The Symbiosity of Creation is a manifesto, which involves — among others  — the following  points:

The Symbiosity of Creation is a change in the position of the author from demiurge to participant.
SC is a shared creation conducted with utter devotion full respect for all participating beings.
SC lacks the possibility of creating only for the time of exhibition — it is necessary to foresee carefully the future of the work.
SC is a process in which everything has meaning, both the decisions of the human-artist and the non-humans participating in the process — the decisions of both parties have a creative influence on one and other, and it does not matter which decisions are more important.

Other important works of Elvin Flamingo include • The Language of Stray Bodies, • Self Cells Portrait, • New-Bio-Territories, • We—The Common Body, • After Humans, the Biocorporation, • Reconstruction of Non-human Culture.

In 2021 Elvin Flamingo started to work on Plant~Animals ~ Symbiosity of Creation in cooperation with Xavier Bailly Ph.D, which premiered at the program of Ars Electronica, Linz, Austria in 2021.

Elvin Flamingo (prof. ASP dr hab. Jarosław Czarnecki) is also lecturer at the Faculty of Sculpture and Intermedia of the Academy of Fine Arts in Gdańsk, Poland and was the Associate Dean of Intermedia (2016-2019).
* the Actor corresponds with the ANT (Actor Network Theory) by Bruno Latour

 

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Data publikacji: wtorek, 8. Marzec 2022 - 09:35; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 9. Marzec 2022 - 12:39; osoba wprowadzająca: Maria Maja Pega

Transcriptional memory of interferon gamma target genes

Speaker:  dr Wojciech Siwek, Harvard Medical School, USA, ICCVS, University of Gdańsk

Talk:  "Transcriptional memory of interferon gamma target genes"

Time:  25.02.2022, 2:00 pm

Venue:  Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d.  


WSDr Wojciech Siwek graduated from the University of Warsaw. He did his PhD at the International Institute of Molecular and Cell Biology, Warsaw followed by two postdocs at Instituto Gulbenkian de Ciência, Lisbon, Portugal & Department of Biochemistry, University of Oxford, UK. Currently, he is an independent Marie Skłodowska-Curie research fellow at Massachusetts General Hospital, Harvard Medical School, Boston, USA & International Centre for Cancer Vaccine Science, University of Gdańsk. Dr Siwek is interested in epigenetic mechanisms in innate immunity and transcriptional memory.

 

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Data publikacji: wtorek, 22. luty 2022 - 07:35; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 8. Marzec 2022 - 09:26; osoba wprowadzająca: Maria Maja Pega

Metabolic control of helper T cell lineage selection

Speaker:  dr Daniel Puleston, Johns Hopkins University - US

Talk:  "Metabolic control of helper T cell lineage selection"

Time:  03/12/2021, 2:00 pm

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


DanielDan graduated with a bachelor degree from the University of Plymouth (UK) and then followed with a master degree in Integrated Immunology at the University of Oxford. He continued there in the lab of Prof. Katja Simon where he did his PhD, investigating the role of autophagy in T cells. He then moved to Germany for a postdoc at the Max Planck Institute for Immunobiology & Epigenetics in Freiburg where he joined the lab of the Prof. Erika Pearce, the Institute Director, to carry out research in immunemetabolism. Currently, since May 2021, Dan is based at Johns Hopkins University in Baltimore, at the The Sidney Kimmel Comprehensive Cancer Centre.

Dan has a fantastic track record of important awards, including multiple scholarships from the Colleges of the University of Oxford, The Ita Askonas Medal for research in immunology, EMBO post-doctoral fellowship and very prestigious Sir Henry Wellcome Post-Doctoral Fellowship awarded by The Wellcome Trust, to name a few.  

Dan has an even more impressive publication record, having published in the highest-ranked journals, incl. Nature Immunology, Nature Metabolism, Cell Metabolism, Cell Host & Microbe, PNAS, Journal of Clinical Investigation and Autophagy. Recently, his first-author research article appeared in Cell. Apart from this, Dan has two patents resulting from his work in the topic of immune modulation, he was also a secretary of the Oxford Immunology Group, and acted as a Guest Associated Editor for Frontiers in Immunology. Finally, he is also involved in the admission process for the Integrated Immunology programme at the University of Oxford.

 

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Data publikacji: czwartek, 28. Październik 2021 - 06:39; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 8. Marzec 2022 - 09:26; osoba wprowadzająca: Maria Maja Pega

Legume tasters: The panoply of symbiotic rhizobia host preference

Speaker:  prof. Alessio Mengoni,  University of Florence, Italy

Talc:  "Legume tasters: The panoply of symbiotic rhizobia host preference"

Time:  17/12/2021, 9:00 am

Venue:  Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


AMBio: Alessio Mengoni graduated in biological sciences in 1997 and obtained a PhD in genetics from the University of Pavia in 2000. He is associate professor of Genetics, qualified as full professor, at the Department of Biology of the University of Florence and has been visiting professor at the Intercollegiate Faculty of Biotechnology MUIG & GU, Gdansk, Poland and at the School of Sun-Yat Sen University, Guangzhou, China. He holds courses in genetics, genetic engineering, genomics and systems biology in the degree programs in Biotechnology and Biology. Main research interests deal with the study of interactions between plants and microorganisms, in particular related to plant growth-promoting bacteria and plant microbiome for applications in agricultural and environmental biotechnology. He is the author of over 170 scientific articles, a patent and founding partner of a spin-off company of the University of Florence for microbiological and genetic analysis (EcolGene Srl). Bibliometric indices: h index = 37, 4105 total citations (Scopus database, October 2021). He has been PI and partner in the last 5 years of various national and international projects, including a Italian Ministry of Agriculture funded project on bioinoculants (MICRO4Legumes), a project on microbial genomic diversity of the National Research Plan in Antarctica (ANTreN), a soil metagenomics project (METATRACK, CR Firenze Foundation), a project on the microbiome of patients affected by Cystic Fibrosis (Italian Cystic Fibrosis Research Foundation), and two H2020 projects on plant bioinoculants (SIMBA) and International Space Station microbiota (BIOWYSE).

AbstractMutualistic interactions have great importance in biology and are key to either macro- and micro-ecosystems functioning, from biogeochemical cycles to the animal and plant microbiome. Many studies have been performed to investigate the molecular aspects of mutualism, however, the genetic repertoire needed for efficient association with host by the microbial symbionts is still poorly understood. Several studies highlighted that the expression of the desired phenotype in the host resides in species-specific, even genotype-specific interactions between the symbiotic partners. Consequently, there is a need to dissect such an intimate level of interaction, aiming to identify the main genetic components in both partners playing a role in symbiotic differences/host preferences [1]. The rhizobia are an exemplary model of microbial mutualist. They are facultative mutualist partners of leguminous plants, with which they establish nitrogen-fixing symbioses.
By applying complementary approaches spanning from computational reconstruction of metabolic interactions to transcriptomic and comparative genomic analyses, we dissected genotype-by-genotype interactions in the model symbiotic partnership between the rhizobium Sinorhizobium meliloti and the host plant (Medicago spp.).
Results from integrated rhizobium-plant genome-scale metabolic model [2], genome-wide association [3] and comparative transcriptomic analyses [4] of late and early stages of symbiosis will be presented and discussed in the light of explaining and exploiting the large genomic diversity rhizobial symbiont populations in the perspective of improving microbial inoculants formulations in sustainable agriculture practices.

 

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Data publikacji: środa, 27. Październik 2021 - 07:27; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 8. Marzec 2022 - 09:26; osoba wprowadzająca: Maria Maja Pega

On Brains and Vessels: How perivascular fibroblasts contribute to ALS neurodegeneration

Speaker: Dr Sebastian Lewandowski

Talk: "On Brains and Vessels: How perivascular fibroblasts contribute to ALS neurodegeneration"

Time: 15.10.2021, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


SlBio: Dr Lewandowski’s research aims to explain the interdependence between the neuronal and vascular cells. His recent work has shown that brain vascular fibroblasts are activated before the onset of neuroinflammation and neurodegeneration in ALS (Månberg et al 2021). His future studies in ALS could help to redefine the mechanisms of ALS etiology, clinical prognosis and therapy. Dr Lewandowski is a member of the Swedish Medical Association, Swedish Society for Neuroscience and a steering group member of the junior faculty at the Karolinska Institute. He has received grants for his ALS research from the Ulla-Carin Lindquist Foundation, the Åhlens Foundation, and the Olle Engkvist Byggmästare Foundation. He received his undergraduate degree from the University of Gdansk and obtained his PhD in molecular biology from the Nencki Institute of Experimental Biology in Warsaw. He performed his postdoctoral training at laboratory of Prof. Ulf Eriksson at the Karolinska Institute.

Abstract. Although the core symptoms of ALS feature rapid, degeneration of motor neurons, we still know little how other cells including blood vessels contribute to ALS etiology. Our work shows that cerebral perivascular fibroblast cells become active long before the onset of neuroinflammation and remodel perivascular spaces with specific collagen and chemokine proteins in ALS mouse models and sporadic ALS patients (Månberg et al. Nature Medicine 2021). Targeted plasma proteomics of 452 ALS patients showed that perivascular fibroblast specific proteins increase vastly outperforms current standards of prediction for patient survival. We believe our results provide a novel conceptual framework to re-evaluate cellular contributions to etiology and dynamics of ALS neurodegeneration. Since enlarged perivascular spaces are repeatedly observed in aging, dementia and other neurological disorders, perivascular fibroblast cell activity could represent a common mechanism in cerebral injury response.

 

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Data publikacji: środa, 20. Październik 2021 - 10:13; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 8. Marzec 2022 - 09:27; osoba wprowadzająca: Maria Maja Pega

Academic basic research vs. big pharma R&D- similarities and differences based on my career transition from postdoc to early drug discovery at GlaxoSmithKline

 

Speaker: dr Maja Firczuk

Talk: "Academic basic research vs. big pharma R&D- similarities and differences based on my career transition from postdoc to early drug discovery at GlaxoSmithKline" 

Time: 7 may 2021, 9:00 am.

Venue: Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d.  


  .

I have completed all my higher education at MWB in Gdansk. I have gained an extensive expertise in biochemistry during my PhD on Hsp70 protein systems, in the group of prof. Marszalek. In 2007 I have started postdoctoral research in systems biology of eukaryotic mRNA translation pathway, first at University on Manchester then at Warwick University. In 2018 I decided to have a career change and moved to work as a biochemist in early drug discovery at GSK.

In my talk I want to share learnings form my career journey and give you an overview of drug discovery process.

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Data publikacji: środa, 2. Czerwiec 2021 - 12:52; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 2. Czerwiec 2021 - 12:53; osoba wprowadzająca: Maria Maja Pega

Neoantigen discovery & proteomics development at International Centre for Cancer Vaccine Science

Speaker: Dr Sachin Kote

Talk: "Neoantigen discovery & proteomics development at International Centre for Cancer Vaccine Science"

Time: 11.06.2021, 9:00 am

Venue: Online in the "IFB seminars" group of MsTeams. Group password: ypidr3d.


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I am acting team leader of the chemical biology group at the International Centre for Cancer Vaccine Science (ICCVS). I am currently leading the neoantigen discovery/immunopeptidomics projects and proteomics development at ICCVS, University of Gdansk, Poland (www.iccvs.ug.edu.pl) since 2018.

I have specialized in peptidomics, proteomics, and cancer vaccine science. I have been working in the field of proteomics concerning health, environment, and safety for the past 12 years. I started my research career as a research project assistant in the proteomics laboratory at the National Chemical Laboratory (NCL), India. Herein, I have developed a strong interest in proteomics, mass spectrometry (MS), and biomarker discovery. Afterward, I moved to Italy for doctoral studies focusing on invitro and invivo nano-bio-interactions, biomarker findings upon nano-exposure, and nanotoxicology using advanced proteomics tools. I have completed my doctoral studies with an excellent Ph.D. award from the University of Salento, Lecce, Italy. Later on, I moved to north Italy for my first postdoctoral studies at the Istituto Italiano di Tecnologia (IIT), Genova, Italy. During my tenure, I developed biological/protein nanoparticles for the safe delivery of nanomedicine applications. In the second but very challenging project, I have developed a dissolution test for risk assessment nanomaterials. I am proud to say that our development of dissolution test is included in the nano-regulatory guidelines i.e., The Organization for Economic Co-operation and Development (OECD, ENV/JM/MONO, 2020, 9) guidelines. These guidelines are applicable in 36 industrialized countries in North and South America, Europe, Asia, and the Pacific.

Additionally, I have a background in Bioinformatics, Clinical Research & Clinical Data Management (CRCDM), and Diploma in Medical Laboratory Technology (DMLT).

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Data publikacji: środa, 2. Czerwiec 2021 - 10:49; osoba wprowadzająca: Monika Sączewska Ostatnia zmiana: wtorek, 8. Marzec 2022 - 09:27; osoba wprowadzająca: Monika Sączewska

Immunopathogensis of dengue; lessons for COVID-19?

 

Speaker: prof. Neelika Malavige (Department of Immunology and Molecular Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka)

Talk: „Immunopathogensis of dengue; lessons for COVID-19?”

Time: 12 March 2021, 9:00 am

Venue: Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d.


prof. Neelika MalavigeNeelika Malavige is a Professor and Head of the Department of Immunology and Molecular Medicine at University of Sri Jayewardenepura, a Director of Centre for Dengue Research and an academic visitor at the MRC Human Immunology Unit, University of Oxford. She is also a member of Executive Committee of the International Society of Infectious Diseases.   

Neelika has obtained medical training and qualifications through University of Colombo, Sri Lanka, Royal College of Physicians, UK and European Academy of Allergology and Clinical Immunology. She did her PhD at the University of Oxford, investigating immune responses to Varicella Zoster virus, having received a Commonwealth Scholarship. She is currently both a scientist and a practising clinician with interest in infectious diseases and allergies. Neelika has obtained research funding of around $ 2 mln and with that support she set up and developed the Centre for Dengue Research at the University of Sri Jayewardenepura. 

Neelika’s current research interest involve immune responses to Dengue virus and biomarker identification; she is also running clinical trials to reduce vascular leak in severe disease. With the onset of the COVID-19 pandemic, Neelika and her team have been also investigating humoral and cellular responses to SARS-CoV2 and sequencing the viral strains.

She has published extensively on Dengue, VZV and now also on COVID-19 in prestigious journals, including Nature Communications, Scientific Reports and PLoS NeglectedTropical Diseases. She has been awarded countless excellence research awards and multiple awards for quality in research supervision. She has been involved in science popularisation, has been proclaimed a “role model” for Women in STEM and has recently won the title of “The most inspiring woman of the year” in Sri Lanka.

 

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Data publikacji: piątek, 5. Marzec 2021 - 06:49; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 2. Czerwiec 2021 - 12:55; osoba wprowadzająca: Maria Maja Pega

Oxford-AstraZeneca Covid-19 vaccine - questions and answers session

 

Speaker: Dr Adam Ritchie (Jenner Institute, Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford)

Talk: Oxford-AstraZeneca Covid-19 vaccine - questions and answers session

Time: 29 January 2021, 9:00 am

Venue: Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d.


Dr Adam RitchieDr Ritchie completed his Bachelor of Science degree in Medical Microbiology and Immunology (2001) and PhD in Immunology (2005), both at the University of New South Wales in Australia. His doctoral research involved investigation of modulation of immune responses by Pseudomonas aeruginosa. After his PhD, he moved to the University of Oxford, working as a postdoctoral researcher in infection risk of blood products, which focused on malaria and variant Creutzfeldt–Jakob disease. Then, he followed with a post-doctoral research position in HIV/AIDS immunology at the Weatherall Institute for Molecular Medicine, University of Oxford as part of the Centre for HIV/AIDS Vaccine Immunology (CHAVI) consortium (2008-2012). During the time he coordinated the CHAVI002 study into individuals resistant to HIV infection in cohorts in the UK and Uganda.

From 2011 to 2017 Dr Ritchie was the Lecturer in Science and Public Policy at the Blavatnik School of Government, a new department at Oxford that he helped establish. Here he taught public policy students and policy makers how to work with scientific evidence, including preparing for and responding to pandemics.

Currently, he is working at the Jenner Institute, University of Oxford as a Senior Project Manager in Vaccine Development and is part of the Oxford COVID Vaccine Trial Group. Initially working on Rabies vaccine from 2017, he set up and manages phase I clinical trials for this vaccine in the UK and Tanzania. In 2020 his role changed due to the pandemic; he was instrumental in developing and delivering the manufacturing process for the ChAdOx1 nCoV-19 vaccine. This included setting up the Manufacturing consortium now producing the vaccine under licence with AstraZeneca, obtaining a UK government commitment of £65 million support for manufacturing, and managing £15 million of that budget.

Dr Ritchie is also actively involved in multiple non-research roles at Oxford, including as the Senior Admissions Adviser for Blavatnik School of Government, and as a Lecturer in Human Science at St Catherine’s College. He holds a Post-Graduate Diploma in Learning and Teaching in Higher Education at the University of Oxford and the Higher Education Academy (2013). He is a Senior fellow of the Higher Education Academy, and received the St Bonaventure University Medal of Honor (2012) and University of Oxford Teaching Excellence Award (2013) for his contributions to education.

Dr Ritchie has co-authored work published by Journal of Virology, Vaccine, Journal of Clinical Investigation, Retrovirology, Infection and Immunity, etc. His most recent work focusing on the COVID19 vaccine resulted in multiple papers published in The Lancet and Nature Medicine.

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Data publikacji: czwartek, 14. Styczeń 2021 - 13:38; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 15. Styczeń 2021 - 09:59; osoba wprowadzająca: Maria Maja Pega

Regulation of gene expression through biomolecular condensation

 

Speaker: dr Adam Kłosin (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany)

Talk: Regulation of gene expression through biomolecular condensation

Time: 06 November 2020, 9:00 am

Venue: Online in the "IFB seminars" group of MS Teams. Group password: ypidr3d.


Adam KłosinAdam Kłosin is a postdoctoral researcher and a Marie Skłodowska-Curie Fellow at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. In 2016 he completed his PhD in the group of Ben Lehner at the Centre for Genomic Regulation in Barcelona where he studied mechanisms of epigenetic inheritance in Caenorhabditis elegans. He then moved to Dresden to train in the arts of biological phase separation in the group of Tony Hyman. In his research he applies biophysical methods to understand various aspects of gene regulation such as transcriptional initiation and control of protein expression variability. His most recent work demonstrates a very effective mechanism for noise reduction in mammalian cells based on compartmentalisation of a protein via liquid- liquid phase separation. He is currently investigating the role of disordered protein domains in regulating interactions with the DNA in the context of transcriptional initiation.

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Data publikacji: wtorek, 20. Październik 2020 - 10:38; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 20. Październik 2020 - 10:41; osoba wprowadzająca: Maria Maja Pega

Genome editing in mitochondria: past, present and future

Speaker: dr Michał Mińczuk (MRC Mitochondrial Biology Unit, University of Cambridge)

Talk: Genome editing in mitochondria: past, present and future

Time: 06 March 2020, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


MMMitochondria are essential for human life. They are complex, compartmentalised organelles that form a dynamic network throughout the cell, host crucial metabolic processes vital for energy provision, and are central to cell fate decisions. Mitochondria contain multiple copies of their own genome, the mtDNA, that encodes the core subunits of the oxidative phosphorylation system. Mutations in protein or RNA coding genes of mtDNA are the most frequent cause of mitochondrial disease. These disorders are currently incurable and effectively untreatable, with heterogeneous penetrance, presentation and prognosis. In most cases, mutant and wild-type mtDNAs coexist within a single cell, resulting in heteroplasmy. The selective elimination of mutant mtDNA, and consequent enrichment of wild-type mtDNA, can rescue pathological phenotypes in heteroplasmic cells. In our work, we have developed mitochondrially targeted zinc finger-nucleases (mtZFNs) for degradation of mutant mtDNA through site-specific DNA cleavage. We have successfully used mtZFNs to target and cleave mtDNA harbouring disease-associated point mutations or large-scale deletions in vitro. More recently, we exploited a unique mouse model that recapitulates common molecular features of heteroplasmic mtDNA disease in cardiac tissue: the m.5024C>T tRNAAla mouse. Through application of mtZFN delivered systemically by adeno-associated virus (AAV), we induced specific elimination of mutant mtDNA across the heart, coupled to a reversion of molecular and biochemical phenotypes. These recent findings constitute proof of principle that mtDNA heteroplasmy correction using programmable nucleases could provide a therapeutic route for heteroplasmic mitochondrial diseases of diverse genetic origin.

WebPage

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Data publikacji: piątek, 6. Marzec 2020 - 06:41; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 6. Marzec 2020 - 06:56; osoba wprowadzająca: Maria Maja Pega

Towards a HIV cure: in which cells is the virus hiding and how to inactivate integrated HIV genomes

Speaker: prof. dr Ben Berkhout (Laboratory of Experimental Virology, Amsterdam UMC)

Talk: Towards a HIV cure: in which cells is the virus hiding and how to inactivate integrated HIV genomes

Time: 03 April 2020, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


BBWe can successfully treat HIV-infected individuals with multiple antiviral drugs, but we cannot cure them as the virus hides in certain cells from which it rebounds after therapy is stopped. A better description of this cellular reservoir has been the Holy Grail of HIV cure research for many years. We could confirm that HIV DNA is quite profoundly enriched in a very small subset of T cells that express the CD32a marker. This is surprising as CD32a is abundantly expressed and functional as Fcgamma receptor on e.g. B cells, but there is a very small T cell subset that also express this surface marker. Thus, cure approaches should be directed towards these CD32a-positive T cells. We developed the CRISPR-Cas technology for a direct attack on the integrated HIV DNA genome. The underlying mechanism of HIV inactivation will be discussed. We propose to develop CD32a-targeting lentiviral vectors that encode these optimized CRISPR-Cas reagents.

Ben Berkhout studied molecular biology at the Leiden University (1976-1981), and obtained his PhD in 1986 at the same university on a research project concerning the regulation of gene expression in RNA bacteriophages, in particular translational control by means of RNA structure. He performed postdoctoral research at the Dana Farber Cancer Institute of the Harvard Medical School in the field of molecular immunology (1986-1989) and initiated HIV-1 research at the National Institutes of Health, Bethesda (Department of Molecular Microbiology, 1989-1991). Ben Berkhout initiated a molecular virology research line in 1991 upon his return to the Netherlands and he has been at the Academic Medical Center (AMC) of the University of Amsterdam since then. He became Head of the Laboratory of Experimental Virology and was appointed as Professor of Human Retrovirology in 2002. Ben Berkhout is editor-in-chief of Virus Research, editor for several journals (Retrovirology, Journal of Biomedical Science, Journal of Biological Chemistry, Virology Journal) and editorial board member for many more. He successfully supervised 46 PhD students and was a member of 131 other PhD thesis committees. Ben Berkhout has published over 520 peer-reviewed manuscripts on diverse topics concerning HIV-1 replication (mechanism of transcription, reverse transcription, RNA-regulated functions), virus evolution (both as a research tool and the underlying molecular mechanisms of drug-resistance), virus discovery (human coronavirus NL63), new antiviral therapeutic strategies (RNA interference, CRISPR-Cas) and HIV-1 vaccine design (improved Env protein immunogen design and conditional live-attenuated HIV-1). His work received >18,800 citations and he has an H-index of 67. Ben Berkhout received the Retrovirology Prize 2008 for his pioneering research on the structure and function of the HIV-1 RNA genome.

 

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Data publikacji: wtorek, 3. Marzec 2020 - 09:35; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 3. Marzec 2020 - 09:46; osoba wprowadzająca: Maria Maja Pega

How photoheterotrophic bacteria can challenge our understanding of carbon cycle

Speaker: dr Katarzyna Piwosz (Centre Algatech, Institute of Microbiology, The Czech Academy of Sciences, Trebon)

Talk: How photoheterotrophic bacteria can challenge our understanding of carbon cycle

Time: 28 February 2020, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


KaisaMy main scientific interest is on ecology of aquatic microorganisms. Aquatic microorganisms: bacteria, algae and heterotrophic protists, are the key players in energy transfer and element cycling in freshwater and marine habitats. These processes are vital for sustaining aquatic ecosystem and the entire biosphere. My research includes investigation of diversity, distribution, dynamics and activity of bacteria, algae and heterotrophic protists in their natural environments. I graduated from the University of Gdansk in Poland. I did my first scientific project for my master thesis at the Institute of Oceanology of the Polish Academy of Sciences. I studied diversity and distribution of algae dwelling in the Arctic Ocean. During hours spent counting different algal species under a microscope, I noticed a plethora of tiny, tiny cells that neither my supervisor, nor any other ecologists could name. This is how I became fascinated with the smallest of microorganisms, for which high quality light microscopy was not enough. Looking for the possibility to identify those cells, I read about use of molecular methods to study microbial diversity. However, to learn these techniques, I had to move to Germany, where I joined Max Planck Research School at Max Planck Institute for Marine Microbiology in Bremen (Marmic). Studying at Marmic and working on my second master thesis at the Alfred Wegener Institute for Polar and Marine Research in Bremerhaven, I learned all the theory and practice I needed to pursue my doctoral study. I returned to the Institute of Oceanology PAS, and, in cooperation with the University of Zurich, I studied small algae and protists in the Baltic Sea. The phylogenetic diversity of algae and protists in the Baltic Sea turned out to be incredible, with thousands of species present in the Gulf of Gdańsk over a year. I discovered groups of protists that no one expected to be present in the Baltic. After I accomplished my PhD, I returned to Polar Regions to answer the question from my first master project: who were the tiny tiny cells in my samples :)

During my work, I participated in scientific cruises to the Baltic Sea, Arctic Ocean and Adriatic Sea. I successfully managed five international scientific projects. I was awarded fellowships and stipends from the EMBL, FEMS, the Director of the Institute of Baltic Sea Research, Warnemünde, Swiss Foundation for Hydrobiology & Limnology, and the University of Zurich, and received four awards from the Director of National Marine Fisheries Research Institute for the publications record. I have been appointed the Ambassador for Poland by the International Society for Microbial Ecology (https://www.isme-microbes.org/). Presently I am a researcher in Institute of Microbiology of Czech Academy of Sciences. My work concentrates on role of photoheterotrophic bacteria in freshwater carbon cycle. There are two known types of photoheterotrophic bacteria: rhodopsin containing and bacteriochlorophylls containing. The former seems to be abundant but slow growing, while the letter are more rare (but still they can make up to 40% of all bacterial abundance) but fast growing, and my current focus lies on them. In my talk, I will present my research on ecology of the bacteriochlorophylls containing photoheterotrophic bacteria in freshwaters: their diversity, seasonal dynamics, activity and interaction with other microbes.  

Website:        Centre Algatech                 About me               Our Team     

 

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Data publikacji: wtorek, 11. luty 2020 - 10:04; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: czwartek, 20. luty 2020 - 06:54; osoba wprowadzająca: Maria Maja Pega

Cold atmospheric pressure plasma – new challenges, new hopes

Speaker: prof. Paweł Pohl (Wrocław University of Science and Technology)

Talk: Cold atmospheric pressure plasma – new challenges, new hopes

Time: 13 March 2020, 09:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


pohlScientific interests: analytical chemistry, atomic spectrometry, optical emission spectrometry, trace analysis, elemental analysis, speciation analysis, food and environmental analytics, spectroscopic diagnostics. 

Plasma (the 4th state of matter) is an ionized gas generated by different processes, including electric discharges or nuclear reactions, and characterized by very high temperatures, i.e., 100,000 K and much more. Natural examples of plasmas are the sun, lightnings on earth, or temporary electrical discharges. Cold atmospheric pressure plasmas (CAPPs) are just partially ionized gases, and ionization degrees in this case are very small (>>0.01%). Such plasmas can be sustained at atmospheric pressure and operated at room temperature, and are characterized by relatively low temperature, or more precisely, several temperatures that are arranged in the following line: Te (electron temperature)>>Texc (excitation temperature of atoms)>Trot (rotational temperature of molecules)@Tg (kinetic temperature of gas molecules, being from few to less than 103oC). In addition, being sustained under atmospheric pressure, CAPP is a rich source of different species, including high energy electrons, ions, excited atoms and molecules, radicals, e.g., O3, NO, NO2, NH, OH, H, UV radiation, and heat. Temperature behavior of CAPP (called non-equilibrium or non-thermal plasma, NTP) in addition to the presence of a “cocktail” of species both determine its features and phenomenal applications. The content and the type of species in CAPP may significantly vary for different sources, and hence, can be modified for specific purposes and applications, showing its great flexibility and diversity. In other words, the concentration and the inherent composition of CAPP can be designed for different intended applications. Some of these applications, including spectrochemical analysis, metallic nanoparticles synthesis, and microorganisms inactivation, will be presented in this lecture, although, it should be noted that the number of possible uses of CAPP is much higher, and go beyond human’s imagination.

 

 

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Data publikacji: wtorek, 28. Styczeń 2020 - 09:37; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: czwartek, 20. luty 2020 - 06:52; osoba wprowadzająca: Maria Maja Pega

RNA decay and surveillance in human mitochondria

Speaker: dr hab. Roman Szczęsny (IBB PAN)

Talk: RNA decay and surveillance in human mitochondria

Time: 06 December 2019, 09:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


rszDr Roman Szczesny graduated from the University of Warsaw in 2004 and joined a PhD programme at the Institute of Biochemistry and Biophysics, PAS. In his thesis he showed that human RNA helicase SUV3 is an essential enzyme for decay and surveillance of mitochondrial RNA (mtRNA). He also described cell death pathways that are activated upon SUV3 silencing. During that time he received several scholarships to work in France and Finland. After obtaining his PhD, he continued to work on mtRNA decay. He supervised the project that led to the identification of the long sought mitochondrial ribonuclease – PNPase, and the discovery of new structures named D-foci where mtRNA degradation occurs. In 2009 he joined Andrzej Dziembowski’s laboratory where he studied mechanisms responsible for RNA surveillance. Having established his group at the Institute of Biochemistry and Biophysics PAS in Warsaw he continues his research into the metabolism of human mitochondrial RNA. His main focus is unraveling mitochondrial gene expression regulation by identification and functional analysis of novel factors engaged in the process. In his research he combines molecular biology, biochemistry and high-throughput methods, including genome-wide siRNA screenings, which provide broad insight into various steps of mitochondrial gene regulation.

Mitochondria are organelles present in most eukaryotic cells that play a vital role in maintaining cellular homeostasis. The function of these organelles depends on the crosstalk between two genomes: nuclear and mitochondrial. Most of the proteins present in mitochondria are encoded in the nuclear genome and are imported into mitochondria upon synthesis in the cytoplasm. Nevertheless, 13 proteins encoded within the mitochondrial genome are essential for human as they are key components of the respiratory complexes. Since human mitochondria seem to have limited possibilities to regulate gene expression by altering the transcription initiation rate, posttranscriptional processes, including RNA degradation, are of great importance for proper mitochondrial and cellular homeostasis. The machinery responsible for mitochondrial RNA decay in humans had remained unknown for many years. We have contributed significantly to the identification and description of the RNA-degradation pathways in human mitochondria. This process, its actors, as well as the consequences of its dysfunction on cellular homeostasis, will be presented.

 

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Data publikacji: wtorek, 3. Grudzień 2019 - 11:20; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 3. Grudzień 2019 - 11:24; osoba wprowadzająca: Maria Maja Pega

Contagion, 15 years on

Speaker: Gina Czarnecki

Talk: Contagion, 15 years on

Time: 29 November 2019, 09:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


GinaGina Czarneckis’ multi-disciplinary arts practice involves the creation media installation video, sculpture, participatory and site specific works that sit at the intersection of art, design, technology and science. Born in Immingham 1965, Gina studied Fine Art at Grimsby School of Art and went on to her BA Hons course at Wimbledon School of Art 1984-7. She started her professional career making animated film and video in the 1980s whilst studying painting. After graduating she developed this into combining live action and drawing whilst working at the London Film-Makers Co-op, running the workshop until 1991. Her postgraduate in Duncan of Jordanstone, Dundee, Scotalnd, (91-2) took her work in film and video through to 3D and computer environments. From 2009 her work developed into participatory sculptures, using biomedical materials and processes, worked on community projects that have helped to shape and transform new hospitals and worked to develop new systems for science engagement and bio-art (Heirloom 2016) and more recently working on the intersection of product design, engineering and business with her project/product ‘Koffin’and ‘Who we are Now”. 2018. Ginas work has been exhibited internationally at venues including Brisbane International Arts Festival, Ars Electronica, Linz, Lumiere, UK, Sundance Film Festival & retrospective & monograph exhibitions include ‘Humancraft ‘ moving image Centre, New Zealand, (2005) and the Bluecoat, Liverpool (2010) She was awarded a Creative Scotland Award (2002) Fleck Fellowship Banff (2004) Best Australian/New Zealand Dance Film (2005) and numerous other prizes. Her work is in both public and private collections.
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Data publikacji: piątek, 22. Listopad 2019 - 08:19; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 22. Listopad 2019 - 08:19; osoba wprowadzająca: Maria Maja Pega

Research ethics: from dilemmas to solutions in scientific practice

Speaker: Dr Francisco Javier Castro-Toledo (Universidad Miguel Hernández de Elche / UMH · CRIMINA. Center for the Study and Prevention of Crime)

Talk: Research ethics: from dilemmas to solutions in scientific practice

Time: 21st February 2020, 09:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


FJCTDr. Francisco Javier Castro-Toledo holds a degree in Philosophy, a master's degree in moral philosophy and holds a PhD from Miguel Hernández University in Elche. He completed his doctorate in July 2018 with the defense of a doctoral thesis funded by the Spanish Institute of Cybersecurity (INCIBE) which was qualified with “cum laude”. Since 2013 he has participated as a researcher, teacher and manager of European R&D projects at the CRÍMINA center for the study and prevention of crime at the UMH under the supervision of Professor Dr. Fernando Miró Llinares, and since 2018 he has been assistant professor in the Department of Legal Science at the Miguel Hernández University in Elche and co-founder CEO of Plus Ethics: a spin-off of the UMH and CRIMINA dedicated to providing ethical and legal support for both public policies and R&D projects.

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Data publikacji: wtorek, 19. Listopad 2019 - 11:41; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 19. Listopad 2019 - 11:56; osoba wprowadzająca: Maria Maja Pega

The essential role of Th17/Treg cells in inflammation

Speaker: Zhi Jane Chen, Associate Professor (Tenure Track) of immunology in Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.

Talk: The essential role of Th17/Treg cells in inflammation

Time: 25th October 2019, 09:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


She graduated from Beijing Medical University (current name: Peking University Health Science Center). She carried out her Ph.D study at the Turku Centre for Biotechnology, University of Turku, Finland. During 2005-2007, she was a postdoctoral fellow at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)/NIH, USA. In 2008-2010, she received a Postdoctoral Fellowship from the Academy of Finland and worked in the Faculty of Medicine, University of Turku. In 2012, she was awarded as an Academy of Finland research fellow, became a principle investigator and group leader working at the Turku Centre for Biotechnology, University of Turku. In 2014, she earned Docentship in Immunology from Faculty of Medicine, University of Turku and started independently supervising Ph.D students.  In 2018, she joined the International Centre for Cancer Vaccine Science (ICCVS), University of Gdansk as a group leader. At the end of 2018, she was appointed as an Associate Professor in University of Oulu, Finland.  Her research focuses on understanding the role of Th17 and Treg cells in regulating the inflammatory/autoimmune and tumorigenesis. Her group studies Th17 and iTreg differentiation at multiple levels from mouse to human and integrate the results to build a comprehensive view of the processes.

 

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Data publikacji: piątek, 18. Październik 2019 - 08:50; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 19. Listopad 2019 - 11:56; osoba wprowadzająca: Maria Maja Pega

α-subunits of voltage-gated channels in vertebrates development and disease

Speaker: prof. Vladimir KorzhInternational Institute of Molecular and Cell Biology, Warsaw, Poland

Talk: α-subunits of voltage-gated channels in vertebrates development and disease

Time: 20th September 2019, 14:00 pm

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


KorzchKcnb1-containing voltage-gated potassium channels consist of two types of α-subunits: (i) electrically active Kcnb1 subunits and (ii) silent or modulatory α-subunits. Voltage-gated potassium channels are viewed as regulators of electrical activity of the plasma membrane in excitable cells, a role that is performed by transmembrane protein domains of α-subunits. Genetic studies revealed a role for this region in human neurodevelopmental disorders, such as epileptic encephalopathy. The N- and C-terminals of α-subunits interact to form the cytoplasmic subunit of heterotetrameric potassium channels that regulate their activity. Subsequent animal studies revealed the developmental functions of Kcnb1-containing voltage-gated potassium channels, illustrating their role during brain development and reproduction. The functions of potassium channels will be discussed in the context of regulatory interactions between electrically active and regulatory α-subunits during zebrafish development.

 

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Data publikacji: wtorek, 30. Lipiec 2019 - 08:49; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 30. Lipiec 2019 - 08:51; osoba wprowadzająca: Maria Maja Pega

Evolutionary and medical implications of the huge diversity of surface polysaccharides in the Enterobacteriales

Speaker: Dr Rafał Mostowy, Group Leader in Microbial Genomics, MCB UJ, Honorary Research Fellow, Imperial College London

Talk: Evolutionary and medical implications of the huge diversity of surface polysaccharides in the Enterobacteriales

Time: 14th June 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


mostowy

Dr Rafał Mostowy studied theoretical physics at the Jagiellonian University and the University of Copenhagen, after which he pursued doctoral studies in evolutionary biology at ETH Zurich. In 2012, he became a postdoctoral fellow at Imperial College London to study evolutionary dynamics of a major bacterial pathogen, Streptococcus pneumoniae. During this time, he developed interest and expertise in genetics of bacterial surface polysaccharides, both in Gram-positive and Gram-negative bacteria. In 2019, he moved from the University of Oxford to Jagiellonian University in Krakow to start his own lab. The newly founded Microbial Genomics group at the Malopolska Centre of Biotechnology uses bioinformatics, computer simulations and statistical methods to provide insight into emergence of antigenic diversity in bacteria, and the role of bacteriophages therein. This research helps us to understand and predict genetic changes in pathogenic bacteria and thus contribute to the co-creation of next-generation drugs.

 

 

 

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Data publikacji: poniedziałek, 10. Czerwiec 2019 - 14:14; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 11. Czerwiec 2019 - 07:30; osoba wprowadzająca: Maria Maja Pega

Lipid-specific T cells and the skin

Speaker: prof. Graham Ogg, MRC Human Immunology Unit and Oxford University Hospitals, UK

Talk: Lipid-specific T cells and the skin

Time: 24th May 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


oggProfessor Graham Ogg is the Deputy Head of MRC Human Immunology Unit of the University of Oxford and he is based at the Weatherall Institute of Molecular Medicine. Graham is a consultant dermatologist and a scientist. He completed his doctoral training with University of Oxford and his clinical training in Oxford and London. Since, he had numerous prestigious appointments, such as the chairman of British Society of Investigative Dermatology and chairman of British Association of Dermatologists Research Committee. Currently, he is an MRC Programme Leader, National Institute of Health Research (NIHR) Senior Investigator and UK’s Clinical Lead for Dermatology. He is also an editor for JAMA Dermatology, Clinical and Developmental Immunology as well as Clinical and Experimental Dermatology.  

His early pioneering work on MHC tetramers laid foundation to investigating specific T cell responses. His current research interest is the interactions between the cellular immune response and the epidermis. Graham’s research and clinical work is based on the investigations of mechanisms underlying inflammatory skin disease.  Particular areas of focus are the roles of unconventional CD1a-restricted T cells and innate lymphoid cells. Graham’s scientific work is recognised worldwide, and he received multiple awards in recognition of this, including Biomedical Research Centre Principal Fellowship, Pharmacia Allergy Research Foundation Award, Dermatologist International Achievement Award.

 

 

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Data publikacji: czwartek, 16. Maj 2019 - 11:26; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: czwartek, 16. Maj 2019 - 11:27; osoba wprowadzająca: Maria Maja Pega

DNA repair processes as markers for personalized cancer therapies

Speaker: Dr. Pawel Zawadzki, Division of Molecular Biophysics, Adam Mickiewicz University Poznan, Poland

Talk: DNA repair processes as markers for personalized cancer therapies.

Time: 17th May 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


pzPersonalized medicine is an approach to improve treatment of an individual patient by taking into account specific changes in individual’s DNA. One aspect of this is an assessment of DNA repair mechanisms to tailor cancer treatment based on patient genomic profiles. Thus, evaluation of the efficiency of DNA repair provides a unique opportunity to apply targeted cancer therapies. We work on identifying DNA repair pathways involved in cell chemosensitivity by RNAi knockdown screening. We tested RNAi library for genes involved in different DNA repair pathways using the hTERT RPE-1 cell line. Silencing RNA interference (RNAi) of the target DNA repair gene was followed with various drug treatments to identify repair pathway-specific chemosensitivity. For example, we observed that silencing of Nucleotide Excision Repair but not Mismatch Repair drastically increase the sensitivity of the cells to popular chemotherapeutic – cisplatin. In conclusion, poor effectiveness of some repair pathways increase susceptibility to cisplatin. Obtaining this information for individual tumor can potentially help select most effective treatment for patients. We suggest that the comprehensive analysis of DNA repair pathways efficiencies, preferably achieved by cancer whole-genome sequencing could provide a diagnostic tool and should soon be applied in the day-to-day cancer diagnostics.

 

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Data publikacji: środa, 15. Maj 2019 - 07:56; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: środa, 15. Maj 2019 - 09:32; osoba wprowadzająca: Maria Maja Pega

Mixed-Lineage Kinase 4 (MLK4) – a new player in breast cancer progression

Speaker: dr Anna Marusiak (CENT Warszawa)

Talk: Mixed-Lineage Kinase 4 (MLK4) – a new player in breast cancer progression

Time: 5th April 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


marusiakI graduated with a MSc in Medical Biotechnology from the University of Wroclaw. I then moved to the UK where I did my doctoral studies at the University of Birmingham. During PhD I investigated the contribution of fibroblast growth factor receptor (FGFR) to the malignant phenotype of breast cancer cells using a proteomic approach. My postdoctoral fellowship took place at Cancer Research UK Manchester Institute in Signalling Networks in Cancer Group. Since then my work in cell signalling has been focused on the family of Mixed-Lineage Kinases (MLKs) and their contribution to carcinogenesis.

In December 2015 I started a position as a postdoctoral fellow at the Centre of New Technologies in the Laboratory of Experimental Medicine. The grants that I have been awarded, Fuga by NCN and Homing by FNP, allowed me to investigate the role of MLK4 in breast cancer progression. MLK4 is a serine/threonine kinase that plays a role in a variety of cellular processes. According to TCGA, amplification and mRNA upregulation of MLK4 is present in 23% of invasive breast carcinoma and our transcriptomic analysis revealed that it is most abundantly expressed in triple-negative breast cancer subtype. Nevertheless, the role of MLK4 in the pathogenesis of breast cancer has been poorly understood so far. My talk will focus on our recent data where we identified MLK4 as a novel therapeutic target for triple-negative breast cancer.

 

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Data publikacji: wtorek, 12. Marzec 2019 - 08:50; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 12. Marzec 2019 - 08:55; osoba wprowadzająca: Maria Maja Pega

Charging the Code - insights into tRNA Modification Enzymes

Speaker: dr Sebastian Glatt (Max Planck Research Group Leader z Małopolskie Centrum Biotechnologii UJ, Kraków)

Talk: Charging the Code - insights into tRNA Modification Enzymes

Time: 15th March 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


glattMy whole scientific career is driven by a deep fascination for the complex molecular mechanisms that allow cells to reproduce, adapt to changing environmental conditions and differentiate into specialized cell types by the activation of specific gene expression programs. These processes are particularly important in multi-cellular organisms, as each individual cell carries the identical genetic information, but needs to produce selected sets of proteins depending on the specialized function of the respective cell type and different external triggering signals. Protein synthesis can be subdivided into different successive processes, called transcription and translation, which are both susceptible to specific regulatory mechanisms. Whereas, transcription describes the production of mRNA molecules from activated genes by RNA polymerases, the subsequent process describes the translation of mRNA encoded sequence information into correctly assembled chains of linked amino acids. During the final step, these peptide chains fold into their correct and enzymatically active three dimensional structure due to their intrinsic properties or with the help of associated chaperoning factors.

During my doctoral thesis I have been studying the consequences of deregulated protein synthesis, leading to an overproduction of certain proteins that are essential for the development of human squamous cell carcinomas. During my postdoctoral time, I have been involved in different basic research projects that focused on understanding the fundamental structural and functional aspects of transcriptional and translational regulation. In detail, I have been studying the structure and function of specific and general transcription factors, which are needed to recruit RNA polymerases and activate gene transcription. In addition, I have been involved in the structural dissection of RNA polymerases themselves and so called chromatin remodelling complexes, which regulate the access of all the above described factors to their respective DNA binding sites in the context of the tight network of condensed chromatin. For most of the above mentioned projects, I have been involved through direct mentoring/supervision of PhD students or contributed my technical expertise in structural biology and protein biochemistry techniques.

My prime scientific interest focused on the structural and functional characterization of specific regulatory events of the translation machinery. In detail, the speed and continuity at which ribosomes move along mRNAs during the elongation phase of translation varies with the nucleotide sequence, influencing not only the rates but also the folding and stability of the emerging nascent polypeptide chains. As tRNA selection in the A-site of ribosomes is a rate-limiting step during elongation phase, the use of synonymous codons and specific base modifications in the wobble base position of tRNAs influences local elongation speed and aids co-translational protein folding. As errors in these tRNA modifications cascades are causing intellectual disabilities, neurodegenerative diseases and cancers in humans, they have caught my special attention over the last years. Therefore, my Max Planck Research Group at the MCB is continuing previous efforts to understand the structure and function of the highly conserved eukaryotic Elongator complex, responsible for conducting specific chemical modifications in the wobble base position of tRNAs. In detail, we use x-ray crystallography and electron microscopy to obtain snapshots of the involved proteins and try to deduce their biochemical activities from the observed structures. Subsequently, we employ different in vitro and in vivo approaches to validate and challenge our structure based working hypotheses. In addition, together with various national and international collaboration partners we have recently started to work on related tRNA modification pathways and other translation control pathways, that are important for stem cell maintenance and differentiation.

Last but not least, I would like to highlight that these cellular mechanisms under investigation are not only highly conserved, vaguely characterized and extremely complex, but are also of high clinical relevance and importance. Therefore, I believe that the results and scientific insights from our ongoing research projects will pave the way for the development of novel diagnostic and therapeutic strategies to improve the life span and life quality of the affected patients.

 

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Data publikacji: piątek, 15. luty 2019 - 09:57; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 15. luty 2019 - 09:59; osoba wprowadzająca: Maria Maja Pega

Interspecies signaling in plant associated bacteria

Speaker: dr Vittorio Venturi (International Centre for Genetic Engineering and Biotechnology (ICGEB),Trieste, Italy)

Talk: Interspecies signaling in plant associated bacteria

Time: 08th March 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Venturi

dr Vittorio Venturi graduated from Edinburgh University, UK, and received his Ph.D. degree in Microbiology from the University of Utrecht, The Netherlands. During his PhD research he focused in the regulation of iron-transport processes of beneficial plant associated bacteria which promote plant growth; the monopolization of iron nearby plant roots is an important trait which keeps microbial pathogens away. He then moved as a postdoctoral fellow to the International Centre for Genetic Engineering & Biotechnology (ICGEB), Trieste, Italy, where he started investigating intercellular signaling among bacteria. He then went on to become Group Leader at ICGEB continuing his studies on intercellular signaling. He has published over 140 research articles in peer-reviewed international journals. He is interested in (i) how plant associated bacteria undergo interspecies communication and interkingdom signaling with plants and (ii) plant microbiomes and the development of microbial products for a more sustainable agriculture https://www.icgeb.org/vittorio-venturi.html

Abstract: Just like what occurs in humans, plants have been recently recognized as meta-organisms possessing a distinct microbiome that have a close relationship with their associated microorganisms. The plant microbiome presents an additional reservoir of genes that the plant can have access to when needed. Plant health is thought to heavily depend also on its microbiome and signaling among microorganisms is crucial for the establishment of the microbial community. Understanding how bacteria undergo interspecies signaling in the microbiome will be a big challenge for future studies. We are using several rice diseases as a model of interspecies bacterial interactions, which also highlights their role in bacterial plant pathogenicity. In addition, we are designing experiments to begin to understand how beneficial plant associated bacteria communicate and establish multispecies communities. Understanding these signaling pathways will help in devising new ways for a more sustainable agriculture.

 

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Data publikacji: wtorek, 5. luty 2019 - 12:35; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 5. luty 2019 - 12:41; osoba wprowadzająca: Maria Maja Pega

Soft rot bacteria and their interaction with potato

Speaker: Prof. Minna Pirhonen (University of Helsinki)

Talk: Soft rot bacteria and their interaction with potato

Time: 12th April 2019, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


helisinkiMinna Pirhonen is an Associate Professor and University Lecturer at the Department of Agricultural Sciences, University of Helsinki, Finland and a supervisor for Doctoral Programmes in Microbiology and Biotechnology and Plant Sciences at University of Helsinki.  Minna’s main research interest are connected to phytopathology, plant physiology, genetics and molecular microbiology.  She is an author and coauthor of more than fifty research and review publications targeting different aspects of interaction of plant pathogenic and plant associated bacteria with their plant hosts as well as isolation and characterization of soft rot bacteria.

Associate Professor Pirhonen was one of the first scientists (1993) to discover and describe that plant pathogenic bacteria communicate with each other in environment (the mechanism broadly known now as quorum sensing) and that they can globally coordinate their populational response during infection of the host. This fundamental work was a basis to understand that bacteria can be perceived as semi-multicellular organisms living under natural conditions in consortia and “talking to each other all the time”.

 

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Data publikacji: wtorek, 22. Styczeń 2019 - 07:30; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 5. luty 2019 - 12:14; osoba wprowadzająca: Maria Maja Pega

Entry of human coronaviruses

Speaker: Krzysztof Pyrć, PhD, DSc, JU professor (Laboratory of Virology, Jagiellonian University)
http://virogenetics.info/

Talk: Entry of human coronaviruses

Time: 25th January 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


prof. PyrćThe virus entry is one of the key points of the infection, and cell/tissue susceptibility to a large extent determines the nature and severity of the disease. Using a variety of techniques we have mapped the route of entry for several coronaviruses, including human coronavirus NL63 and human coronavirus OC43. Available data on coronavirus’ entry originate frequently from studies employing immortalized cell lines or undifferentiated cells. Here, using the most advanced 3D tissue culture system mimicking the epithelium of conductive airways, we systematically mapped entry of viruses into susceptible cell. Considering low specificity of chemical inhibitors targeting different endocytic pathways, we decided to track the fate of a single virus particle in the cell with confocal microscopy. Obtained results were validated with developed 3D image analysis algorithms and subsequent statistical assessment.

Our results show that HCoV-NL63 virions require endocytosis for successful entry, and interaction between the virus and the receptor molecule triggers recruitment of clathrin. Subsequent vesicle scission by dynamin results in virus internalization, and the newly formed vesicle passes the actin cortex, what requires cytoskeleton rearrangement. Finally, acidification of the endosomal microenvironment is required for successful fusion and release of viral genome into the cytoplasm. On the other hand, HCoV‑OC43 employed a very different route, using caveolin-1-dependent pathway to enter the cell. Surprisingly, the virus was also internalized by macropinocytosis, but this route of internalization did not allow for virus entry and subsequent replication. HCoV‑OC43 trafficking in the cell seems to be carried out along actin filaments. We believe that usage of 3D tissue culture models and an appropriate methodology allowed us to obtain reliable, relevant biological results.

 

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Data publikacji: piątek, 18. Styczeń 2019 - 12:10; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 18. Styczeń 2019 - 12:18; osoba wprowadzająca: Maria Maja Pega

dr Sivakumar Vadivel Gnanasundram (French Institute of Health and Medical Research)

Speaker: dr Sivakumar Vadivel Gnanasundram (French Institute of Health and Medical Research)

Time: 16th November 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


dr gnanasundramDr. Gnanasundram finished his Master’s degree in Microbiology from the University of Madras, India in 2008. He then moved to Indian Institute of Science, India as a Research fellow and worked on novel anti-viral therapeutics using small RNAs targeting Hepatitis C virus RNA translation. For his doctoral degree he enrolled into HBIGS, Heidelberg University, Germany where he worked on Ribosome biogenesis pathway and RNA helicases. He completed his doctoral degree in 2014.  For his post-doctoral work he moved to Dr. Robin Fåhraeus group at INSERM, Paris, France.

His present work involves in understanding the oncogenic mechanisms of the Epstein-Barr virus (EBV)-encoded EBNA1. It has been known for over 50 years that EBV is a human oncogenic virus responsible for app. 2-3% of all cancers but unlike other oncogenic viruses, the underlying molecular oncogenic mechanisms of EBV have largely remained obscure. Transgenic mice models have shown a reverse correlation between the expression of the EBNA1 protein and a lymphoma phenotype. Why less of an oncogenic protein would give more cancer could not be explained until now. It turns out that EBNA1 suppresses its own synthesis in cis in order to minimize the production of antigenic peptides for the MHC class I pathway and thereby helps the virus to evade the immune system. His work that is recently published in Nature Communications shows that the stress caused by this suppression of translation leads to the activation of E2F1 and the induction of c-myc. We speculate that the virus is exploiting a cellular pathway whereby cells senses dysfunctional mRNA translation and compensates by inducing ribosomal biogenesis via c-myc.

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Data publikacji: czwartek, 15. Listopad 2018 - 10:23; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 16. Listopad 2018 - 08:33; osoba wprowadzająca: Maria Maja Pega

Discovering multiple roles for AKT1 in skin barrier function and skin disease

Speaker: dr Ryan O'Shaughnessy (University of London)

Talk: Discovering multiple roles for AKT1 in skin barrier function and skin disease

Time: 19th October 2018, 9:00 am

Venue: Faculty of Chemistry, hall F8


cvg  hbn
Dr Ryan O'Shaughnessy
is a Senior Lecturer in the Centre for Cell Biology and Cutaneous Research. He leads a research programme focused on understanding molecular mechanisms of skin barrier function and through these insights, developing new therapies for diseases of skin barrier function, with particular emphasis on the ichthyoses, eczema and skin cancer.

Ryan completed his PhD in keratinocyte biology at Cancer Research UK, before postdoctoral training at Columbia University, NY and Queen Mary University of London. He started his skin barrier laboratory in 2008 at the UCL Great Ormond Street Institute of Child Health, and in 2012 was the Academic Lead of the Livingstone Skin Research Centre, a research centre dedicated to the study of childhood skin disease. He was awarded a Society of Investigative Dermatology Kligman fellowship in 2002 and the British Society of Investigative Dermatology Young Investigator Award in 2009.

Memberships include the European Society of Dermatological Research and the European Epidermal Barrier Research Network, and the UK Translational Research Network in Dermatology (UK TREND) and he is on the Editorial Board of Experimental Dermatology and on the Committee of the British Society of Investigative Dermatology. 

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Data publikacji: piątek, 5. Październik 2018 - 08:23; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: czwartek, 18. Październik 2018 - 09:12; osoba wprowadzająca: Maria Maja Pega

Protein deubiquitylation controls the degradation of mislocalised secretory and membrane proteins and regulates endoplasmic reticulum function

Speaker: dr Paweł Leźnicki (University of Manchester, Manchester, United Kingdom)

Talk: Protein deubiquitylation controls the degradation of mislocalised secretory and membrane proteins and regulates endoplasmic reticulum function

Time: 23th November 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Leznicki PawelPaweł Leźnicki graduated with an MSc in Biotechnology from the Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Poland, in 2006. He then moved to Manchester, United Kingdom, to work on the mechanisms of post-translational delivery of tail-anchored membrane proteins to the endoplasmic reticulum. He received his PhD degree in Biochemistry in 2010. At that point his research interests shifted towards studying protein degradation mediated by the ubiquitin-proteasome system. He investigated this process and the function of deubiquitylating enzymes initially at the University of Manchester (2011-2013) and then at the MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, United Kingdom, a world-renowned centre for ubiquitylation-oriented research. In 2017 he moved back to Manchester to continue his work on the role of deubiquitylating enzymes in the regulation of intracellular processes.

The ubiquitin-proteasome system is the predominant degradative route for the disposal of defective and/or unwanted proteins in eukaryotic cells. Polypeptides destined for the proteasome-mediated degradation are most often initially marked by covalent conjugation of a small polypeptide, ubiquitin. Ubiquitin can form polymers (ubiquitin chains or polyubiquitin) linked via lysine residues or the N-terminus of a ubiquitin monomer, and the residue used to build such chains defines the functional outcome of protein ubiquitylation. Importantly, ubiquitylation can be reversed by the action of a group of enzymes collectively known as deubiquitylating enzymes (DUBs). By studying the quality control of membrane and secretory proteins destined to the endoplasmic reticulum (ER) we have identified several factors that control the steady-state levels of membrane and secretory proteins that fail to reach the ER. Such mislocalised proteins (MLPs) are routed towards degradation by the BAG6 complex but can be rescued by SGTA, a protein that stimulates MLP deubiquitylation. Further studies defined the molecular basis of these processes. Our subsequent work uncovered an isoform-specific function of a deubiquitylating enzyme, USP35, in apoptosis, lipid metabolism and ER stress. It also opened up new avenues for future work addressing the role of DUBs in controlling the function of intracellular organelles and pathways.

 

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Data publikacji: poniedziałek, 18. Czerwiec 2018 - 09:55; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 18. Czerwiec 2018 - 10:01; osoba wprowadzająca: Maria Maja Pega

Unlocking the clinical utility of genomic biomarkers in ovarian cancer

Speaker: dr Anna Piskorz (University of  Cambridge)

Talk: Unlocking the clinical utility of genomic biomarkers in ovarian cancer

Time: 25th May 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Anna Piskosz
I’m a molecular biologist focus on translational research in high grade serous ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better patient stratification, earlier disease diagnosis, monitoring patient response and improving patient management during the course of treatment. My research interests focus on development and implementation of new genomic technologies with potential application in clinic like shallow whole genome sequencing for copy number alterations detection and detection of mutant tumour DNA in body fluids. In my research I use variety of specimens like tumour tissue and body fluids (blood, plasma, ascites). I have a special interest in molecular characterization of ascites samples. I’m engaged in molecular analysis of samples from several clinical trials (ARIEL2, PISSARO, ICON7, ICON8, MADCaP, PHL-093 Toronto, OZM-061 Toronto) and collaborate with scientists from other research centres: University of Calgary (Canada), NKI (The Netherlands), VU University Medical Centre (The Netherlands), Institute of Cancer Sciences University of Glasgow (UK). I'm lead consultant for the molecular analysis of HGSOC samples in collaborations with the Ovarian Tumour Tissue Analysis (OTTA) and the Multidisciplinary Ovarian Cancer Outcomes Group (MOCOG) consortiums. One of my main aims is to transform HGSOC patients' care in Addenbrooks's hospital through the implementation of real time molecular profiling of every women with HGSOC by setting up workflow between CRUK CI, pathologists, tissue bank and Cancer Molecular Diagnostic Laboratory.

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Data publikacji: piątek, 11. Maj 2018 - 13:40; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 11. Maj 2018 - 13:45; osoba wprowadzająca: Maria Maja Pega

How Art and Design can help Redesign Science itself; both the scientific method and the social embedding of science

Speaker: prof. Roger Malina (The University of Texas at Dallas)

Talk: How Art and Design can help Redesign Science itself; both the scientific method and the social embedding of science

Time: 11th May 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


prof. MalinaRoger Malina is a physicist, astronomer and executive editor of the Leonardo publications at MIT Press. With dual appointments as a professor of arts and technology and a professor of physics at UT Dallas, he focuses on connections among the natural sciences and arts, design and humanitiesHe is a former director of the Observatoire Astronomique de Marseille Provence (OAMP) in Marseille, and member of its observational cosmology group, which performs investigations on the nature of dark matter and dark energy. He is also a member of the Mediterranean Institute for Advanced Study (Institut Méditerranéen de Recherches Avancées, IMERA), an institute he helped to organize. IMERA seeks to contribute to trans-disciplinarity between the sciences and the arts and places emphasis on the human dimensions of the sciences. Malina was also a member of the jury for the Buckminster Fuller Challenge 2011, which awards a prize to those who create strategies with potential to “solve humanity's most pressing problems.” Malina's specialty is space instrumentation. He was the principal investigator for the NASA Extreme Ultraviolet Explorer satellite at the University of California, Berkeley. The satellite was the first orbiting observatory to map the sky in the extreme ultraviolet band. The team at UC Berkeley had to invent new kinds of cameras, telescopes and data analysis techniques. The team was one of the first university groups to take over operation of a NASA satellite and operate it from a university, with teams of students. For 25 years, Malina has been involved with the Leonardo organizations, which his father founded in San Francisco and Paris. The organizations strive to promote work that explores the interactions between the arts and sciences, as well as between the arts and new technologies. Malina earned his bachelor's degree in physics from Massachusetts Institute of Technology in 1972, and his doctorate in astronomy from the University of California, Berkeley in 1979.

 
Wykład zorganizowany we współpracy MWB UG & GUMed z Centrum Sztuki Współczesnej ŁAŹNIA w Gdańsku, odbędzie się w ramach realizowanego na MWB UG & GUMed projektu STARBIOS2 (Horyzont 2020)
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Data publikacji: poniedziałek, 7. Maj 2018 - 12:34; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 7. Maj 2018 - 12:36; osoba wprowadzająca: Maria Maja Pega

Inne oblicze GMO, A.D. 2018

Speaker: prof. Tadeusz Twardowski (Instytut Chemii Bioorganicznej PAN w Poznaniu)

Talk: Inne oblicze GMO, A.D. 2018

Time: 27 kwietnia 2018 r., godz: 9:00

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


https://ug.edu.pl/media/aktualnosci/75653/prof_tomasz_twardowski_o_gmo_ad_2018

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Data publikacji: poniedziałek, 7. Maj 2018 - 12:33; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: poniedziałek, 7. Maj 2018 - 12:33; osoba wprowadzająca: Maria Maja Pega

Targeting mitochondrial DNA in lung diseases.

Speaker: prof. Bartosz Szczęsny (University of Texas Medical Branch at Galveston)

Talk: Targeting mitochondrial DNA in lung diseases

Time: 20th April 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


SzczęsnyDr. Szczesny received his BA, MS, and PhD degrees from the University of Wroclaw, Poland. He completed his post-doctoral training at the University of Texas Medical Branch at Galveston, in the United States, in Dr. Mitra’s laboratory, working on mitochondrial DNA repair. His research training includes positions at Strathclyde University, Glasgow, Scotland; Lund University, Sweden; and University in Louvain la Neuve, Belgium.

Dr. Szczesny is currently an Associate Professor in the Department of Anesthesiology at the University of Texas Medical Branch, and a Staff Scientist at the Shriners Hospital for Children in Galveston, one of the leading pediatric burn centers in the United States. Dr. Szczesny is an expert in mitochondrial DNA damage and repair, and on the signaling of mitochondrial dysfunction in various pathological conditions. His major research interests are mitochondrial dysfunction in acute lung injury and development of new treatment strategy in lung cancer targeting mitochondria/mitochondrial DNA.

 

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Data publikacji: piątek, 23. Marzec 2018 - 13:35; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:47; osoba wprowadzająca: Maria Maja Pega

prof. Alfredo Nicosia, University of Naples

Speaker: prof. Alfredo Nicosia, University of Naples (Chief Executive Officer (CEO) and Co-founder of Nouscom AG)

Talk: Soon

Time: 23th February 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


VG

Prof. Alfredo Nicosia is the Chief Executive Officer(CEO) and Co-founder of Nouscom AG, a biotech company dedicated to the development of next generation immunotherapies to beat cancer (www.nouscom.com). He is also CEO of Reithera srl, a Biotech involved in the development of vector-based anti-infectious vaccines.

Alfredo was a co-founder of Okairos (recently acquired by GSK) and served as the company’s Chief Scientific Officer, contributing to the preclinical and clinical development of a number of vaccines (including vaccines against HCV, Ebola and malaria) and monoclonal antibodies against infectious diseases and cancer.

Alfredo’s experience includes the positions of senior director of the Viral Diseases Vaccine program at Istituto di Ricerche di Biologia Molecolare (IRBM), staff scientist at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and project leader at the Sclavo Research Centre in Siena, Italy.

He has also published over 150 articles in leading journals on a range of subjects, including viral and bacterial infection and vaccines and holds a number of patents and patent applications.

Alfredo holds a degree in chemistry from the University of Rome, Italy and is a full Professor of Molecular Biology at the University Federico II, Naples (Italy).

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Data publikacji: piątek, 26. Styczeń 2018 - 08:00; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:48; osoba wprowadzająca: Maria Maja Pega

To rot, or not to rot: comprehensive view on the interactions of phytopathogenic pectobacteria with plants

Speaker: dr Vladimir Y. Gorshkov (Kazan Institute of Biochemistry and Biophysics)

Talk: To rot, or not to rot: comprehensive view on the interactions of phytopathogenic pectobacteria with plants

Time: 9th March 2018, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


VG

Dr. Vladimir Y. Gorshkov is a Senior Researcher at Federal Research Center: Kazan Science Centre of the Russian Academy of Sciences, Russian Academy of Science in Kazan, and a Senior Lecturer at Kazan Federal University, Russia. His main research interests are connected wiht phytopathology, plant physiology, microbiology and molecular biology. Vladimir defended his Phd thesis entitled “Cell-to-cell communication in the populations of Pectobacterium atrosepticum SCRI1043 during the interaction with host plant and under starvation” in 2009 and since then his major scientific interest is signal exchange between bacteria and host plants during interaction. Vladimir is an expert in molecular aspects of symbiosis and pathogenesis and at the moment serves as a Phd student supervisor of 3 PhD students. He is an author and co-author of more than 20 original research papers. His beloved bug is Pectobacterium atrosepticum and bellowed host plant: potato and tobacco. 

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Data publikacji: piątek, 19. Styczeń 2018 - 13:53; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:48; osoba wprowadzająca: Maria Maja Pega

Gender Gap in Biotechnology - dr Natasza Kosakowska-Berezecka, dr Magdalena Żadkowska (University of Gdańsk, Poland)

Speaker: dr Natasza Kosakowska-Berezecka, dr Magdalena Żadkowska (University of Gdańsk, Poland)

Talk: Gender Gap in Biotechnology

Time: 1 December 2017, 9:00 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Natasz Kosakowska photoNatasza Kosakowska-Berezecka, notka biograficzna

Tenerka umiejętności menedżerskich, wykładowczyni akademicka w Zakładzie Psychologii Międzykulturowej i Rodzaju w Instytucie Psychologii Uniwersytetu Gdańskiego; mediatorka oraz ekspertka ds różnorodności i równowagi praca-dom

Kierowniczka międzynarodowego konsorcjum badawczego PAR Migration Navigator (www.migrationnavigator.org)- WLB_GE "Socio-cultural and Psychological Predictors of Work-Life Balance and Gender Equality- Cross-Cultural Comparison of Polish and Norwegian Families".

Autorka i ekspertka ds. Programu oraz zaleceń organizacyjnych pomocy/ doradztwa personalnego dla kobiet i ich partnerów i Innowacyjnego programu oraz zaleceń organizacyjnych systemu szkoleń adaptacyjnych do pracy (model adaptacji do pracy) w projekcie  "PI – Innowacyjny model godzenia przez kobiety życia zawodowego i rodzinnego" współfinansowanego ze środków Unii Europejskiej w ramach Europejskiego Funduszu Społecznego.

Trenerka nagrodzonego w konkursie na Dobre Praktyki EFS projektu szkoleniowego KiM Kobieta i Mężczyzna Liderami Pomorskich Przedsiębiorstw realizowanym przez Gdańską Fundację Kształcenia Menedżerów.

Ekspertka medialna: Gazeta Wyborcza, Radio Gdańsk, Polskie Radio "Trójka", Newsweek.

Współautorka i koordynatorka wdrażania Gdańskiego Modelu Integracji Migrantów, panel Edukacji Wyższej.
 


Magda Żadkowska photoMagdalena Żadkowska, notka biograficzna

Pracuje jako adiunkt na Uniwersytecie Gdańskim; prowadzi zajęcia z Zarządzania projektami społecznymi, Komunikacji międzykulturowej, Zarządzania różnorodnością w organizacji i Komunikacji interpersonalnej.

Prowadzi zajęcia na studiach podyplomowych MBA: Zarządzanie różnorodnością, Metodologia projektu dyplomowego, Kierowanie zespołem.

Analizuje życie domowe i zawodowe par w Polsce i na migracji. Bada podział obowiązków i negocjowanie godzenia życia zawodowego z rodzinnym.

Ukończyła socjologię na Uniwersytecie Gdańskim i kulturoznawstwo na Uniwersytecie Jagiellońskim. Jest doktorem nauk humanistycznych w zakresie socjologii, obronionym na Uniwersytecie Mikołaja Kopernika w Toruniu. Ukończyła warsztat Kena Cushnera (nauczanie kompetencji kulturowych), ukończyła Szkołę Trenerów TROP (szkolenia oparte na empatii) i kurs trenerów Szkoły dla rodziców. 

Rzeczniczka równouprawnienia i różnorodności, bardzo chętnie angażuje się w różnego rodzaju projekty upowszechniające naukę – jest trenerką biznesową, ekspertką medialną i autorką projektów społecznych.

Trenerka biznesowa, specjalistka ds.  Komunikacji wewnętrznej, Komunikacji międzykulturowej, Zarządzania wartościami, Zarządzania wiekiem, Budowania zespołów, Godzenia życia zawodowego z rodzinnym i Wdrażania elastycznych form pracy.

Autorka i Koordynatorka merytoryczna nagrodzonego przez Ministerstwo Rozwoju Regionalnego w konkursie na Dobre Praktyki EFS 2011 projektu szkoleniowego KiM Kobieta i Mężczyzna Liderami i Liderkami Pomorskich Przedsiębiorstw (5 edycji).

Trenerka  w projekcie KiM Kobieta i Mężczyzna Liderami i Liderkami Pomorskich Przedsiębiorstw.
Liderka badań socjologicznych w międzynarodowym konsorcjum badawczym PAR Migration Navigator (www.migrationnavigator.org)- WLB_GE "Socio-cultural and Psychological Predictors of Work-Life Balance and Gender Equality- Cross-Cultural Comparison of Polish and Norwegian Families".
Autorka metody szkoleń dla par z Godzenia życia zawodowego z rodzinnym.
Badaczka w projekcie "A więc siedzisz w domu, etnograficzne studium pracy wykonywanej z domu", grant Narodowego Centrum Nauki.
Autorka i ekspertka ds. Programu oraz zaleceń organizacyjnych pomocy/ doradztwa personalnego dla kobiet i ich partnerów i Innowacyjnego programu oraz zaleceń organizacyjnych systemu szkoleń adaptacyjnych do pracy (model adaptacji do pracy) w projekcie  „PI – Innowacyjny model godzenia przez kobiety życia zawodowego i rodzinnego” współfinansowanego ze środków Unii Europejskiej w ramach Europejskiego Funduszu Społecznego.
Ekspertka w projekcie "7 kroków do Work-Life-Balance", organizowanego przez Pracodawców Pomorza.
Ekspertka medialna: Gazeta Wyborcza, Radio Gdańsk, Newsweek, TV4.
Wykładała na uczelniach polskich i zagranicznych.
Współautorka i koordynatorka wdrażania Gdańskiego Modelu Integracji Migrantów, panel Edukacji Wyższej.
 

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Data publikacji: środa, 15. Listopad 2017 - 11:47; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:42; osoba wprowadzająca: Elżbieta Moroz

Magdalena Król (Szkoła Główna Gospodarstwa Wiejskiego), Seksmisja w nauce

Speaker: dr hab. Magdalena Król, prof. SGGW (Szkoła Główna Gospodarstwa Wiejskiego, Poland)SGGW logo

Talk: Seksmisja w nauce

Time: 1 December 2017, 9:30 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042


Magdalena Krol photoMagdalena Król, notka biograficzna

Profesor Magdalena Król urodziła się w Płocku. Jest lekarzem weterynarii, doktorem habilitowanym nauk weterynaryjnych, profesorem nadzwyczajnym Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie oraz Kierownikiem Zakładu Fizjologii na Wydziale Medycyny Weterynaryjnej. W 2017 roku była profesorem wizytującym na Uniwersytecie „La Sapienza” w Rzymie. Zajmuje się onkologią eksperymentalną, szczególnie fascynują ją terapie komórkowe i wpływ układu immunologicznego na powstawanie przerzutów nowotworowych.

Odbyła liczne staże naukowe w Holandii, Belgii, Szwecji i USA. Jest laureatką wielu nagród m.in. Stypendium START FNP (2011 i 2012), Stypendium MNiSW dla wybitnych młodych naukowców (2012), Young Investigator Scholarship in Veterinary Medicine ufundowanej przez Pfizer Animal Health (2012),  Nagród Naukowych POLITYKI w kategorii nauka (2013), stypendium habilitacyjnego L’Oreal i Unesco „Dla kobiet nauki” (2013). W 2014 r. została laureatką plebiscytu „Polacy z werwą”, a w 2017 „Człowiekiem roku 2016” w kategorii nauka w plebiscycie „Gazety Wyborczej”.

W ubiegłym roku otrzymała prestiżowy grant Europejskiej Rady ds. Badań (ERC). Dzięki niemu przez pięć lat zespół naukowców będzie realizował projekt badawczy mający na celu wyjaśnienie zjawiska biologicznego „TRAIN” odkrytego przez prof. Magdalenę Król, która chciałaby wykorzystać je w praktyce onkologicznej.

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Data publikacji: środa, 15. Listopad 2017 - 10:56; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:42; osoba wprowadzająca: Elżbieta Moroz

Targeted therapy in mesenchymal diseases - preclinical drug testing in vivo

Speaker: Dr Agnieszka Wożniak (Leuven Cancer Institute, Belgium)

Talk: Targeted therapy in mesenchymal diseases - preclinical drug testing in vivo

Time: 26 May 2017, 9 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58


woźniak

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Data publikacji: środa, 24. Maj 2017 - 13:55; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:43; osoba wprowadzająca: Maria Maja Pega

Mechanisms of RNA-directed DNA methylation

Speaker: dr Andrzej T. Wierzbicki (University of Michigan Department of Molecular, Cellular, and Developmental Biology (MCDB), USA)

Talk: Mechanisms of RNA-directed DNA methylation

Time: 22 May 2017, 15pm

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58


Wierzbicki

RNA-directed DNA methylation is a conserved process where small RNAs target transposons and other sequences for repression by establishing chromatin modifications. A central element of this process is long noncoding RNA (lncRNA) which has been proposed to serve as a binding scaffold for small RNAs and associated proteins. In Arabidopsis thaliana, this lncRNA is produced by a specialized RNA polymerase known as Pol V. Pol V transcripts serve as a binding scaffold for several RNA-binding proteins, which mediate the recruitment of chromatin modifying enzymes. These enzymes contribute to the repression of transposon activity and help determine the boundaries between heterochromatic transposons and their euchromatic environment. RNA-directed DNA methylation has also been implicated in controlling organization of chromosomes, which may explain how it affects expression of distant genes.

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Data publikacji: środa, 24. Maj 2017 - 12:37; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:48; osoba wprowadzająca: Maria Maja Pega

Vascular injury accelerates the onset of ALS neurodegeneration: evidence from mouse models and patients.

Speaker: Sebastian Lewandowski PhD (Karolinska Institute, MBB, Stockholm, Sweden)

Talk: Vascular injury accelerates the onset of ALS neurodegeneration: evidence from mouse models and patients.

Time: 30 June 2017, 9 am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58


Lewandowski

Efficient delivery of oxygen and nutrients is essential for correct brain function. Our studies focus on the mechanisms of vascular injury to explain dysfunction of the blood-brain barrier and decreased cerebral blood flow in patients with amyotrophic lateral sclerosis (ALS). We found that presymptomatic activation of the PDGFC pathway leads to dysfunction of the blood-brain barrier in ALS mouse models and is correlated with younger age at disease onset in mouse models and patients. Vascular injury also leads to dysfunction of the vascular basement membrane where perivascular astrocytes detach from cerebral blood vessels and increase expression of specific extracellular matrix proteins. We found that the increase of vascular basement membrane proteins in plasma of ALS patients is correlated with decreased levels of glucose brain uptake and younger age at disease onset. In summary our findings show that cerebral vessel injury can be a risk factor for young onset of ALS neurodegeneration.

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Data publikacji: środa, 24. Maj 2017 - 12:37; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:49; osoba wprowadzająca: Maria Maja Pega

Otwarty dostęp do publikacji i danych naukowych

Speaker: dr Marta Hoffman-Sommer (Interdyscyplinarne Centrum Modelowania Matematycznego i Komputerowego Uniwersytetu Warszawskiego, Platforma Otwartej Nauki)

Talk: Otwarty dostęp do publikacji i danych naukowych

Time: 21 April 2017, 9.15am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar

Po wykładzie dyskusja panelowa z udziałem zaproszonych gości. Planowany czas trwania (9.15-11.00).

http://biotech.ug.edu.pl/media/aktualnosci/65077/otwarta_nauka_szanse_-_wyzwania_-_kierunki


sommer

Marta Hoffman-Sommer jest absolwentką Międzywydziałowych Indywidualnych Studiów Matematyczno-Przyrodniczych na Uniwersytecie Warszawskim. Stopień doktora nauk biochemicznych (2007) uzyskała w Instytucie Biochemii i Biofizyki PAN w Warszawie na podstawie badań nad transportem wewnątrzkomórkowym u drożdży. Staż podoktorski odbyła na Uniwersytecie Humboldtów w Berlinie (2010-2012) w dziedzinie modelowania matematycznego w biologii. Od roku 2012 pracuje w Interdyscyplinarnym Centrum Modelowania Matematycznego i Komputerowego Uniwersytetu Warszawskiego, gdzie w ramach Platformy Otwartej Nauki zajmuje się kwestiami dotyczącymi otwartej nauki, otwartych danych badawczych i zarządzania danymi, koordynuje ogólnopolskie Repozytorium Otwartych Danych RepOD i reprezentuje Krajowe Biuro Otwartego Dostępu projektu OpenAIRE.

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Data publikacji: środa, 12. Kwiecień 2017 - 08:57; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:49; osoba wprowadzająca: Maria Maja Pega

Forward genetic studies of gene essentiality and sporulation in Clostridium difficile

Speaker: dr Marcin Dembek (Institute for Cell and Molecular Biosciences, Newcastle University, UK)

Talk: Forward genetic studies of gene essentiality and sporulation in Clostridium difficile

Time: 24 March 2017, 9am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


,kj

Marcin Dembek obtained his master’s degree in 2009 at the Intercollegiate Faculty of Biotechnology UG-MUG while studying the potential application of B. subtilis spores as an antigen delivery platform for use in the development of an oral vaccine against Helicobacter pylori. He went on to secure a Wellcome Trust PhD scholarship at Imperial College London to develop genome-wide approaches to studying sporulation and germination in Clostridium difficile. In 2013, he took up a post-doctoral position at the Jenner Institute, University of Oxford to work on the development of novel vaccine candidates against malaria before being offered a research associate position in Dr. Paula Salgado’s lab at Newcastle University where he studies the structure and function of potential drug targets in C. difficile. His current work is primarily aimed at understanding the organisation of the ‘molecular machinery’ involved in the engulfment stage of sporulation.

Dr Dembek is a member of the Microbiology Society and an active part of the Polish scientific community in the UK. In 2014, he co-founded Getty Science, an online publication platform aimed at researcher who wish to share their work through creative writing and illustration, as part of a close collaboration with the annual ‘Science. Polish Perspectives’ meeting.

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Data publikacji: poniedziałek, 6. Marzec 2017 - 13:08; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: piątek, 23. Marzec 2018 - 13:48; osoba wprowadzająca: Maria Maja Pega

Structural basis of DNA replication and repair in human mitochondria

Speaker: dr Michał Szymański

Talk: Structural basis of DNA replication and repair in human mitochondria

Time: 13 January 2017, 10am

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


,kjMichal Roman Szymanski is a Research Scientist in the Department of Pharmacology at the University of Texas Medical Branch, Galveston, Texas. He obtained a Bachelor of Science in Biochemical and Biophysical Sciences from the University of Houston in 2007 working on structural and functional characterization of HMW1B, a membrane protein from Haemophilus influenzae. In 2011, he received his PhD degree in Biochemistry from the University of Texas Medical Branch at Galveston, Texas for the work on “Helicase initiated assembly of macromolecular machines involved in DNA replication and repair”. In 2012-13, as a Jeane B. Kempner Postdoctoral Fellow, he studied the assembly of E.coli primosome with Professor Wlodek M. Bujalowski. In 2013 he moved to the Pharmacology Department at UTMB to study the structural basis for human mitochondrial DNA replication and antiviral drug toxicity.

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Data publikacji: poniedziałek, 9. Styczeń 2017 - 13:49; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:45; osoba wprowadzająca: Maria Maja Pega

Inflammatory signalling from the endocytic pathway

Speaker: prof. dr hab. Marta Miączyńska (Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie)

d

Talk: Inflammatory signalling from the endocytic pathway

Time: 20 January 2017

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


gfAbsolwentka Uniwersytetu Jagiellońskiego (kierunek biologia molekularna, 1992), uzyskała stopień doktora w dziedzinie genetyki na Uniwersytecie Wiedeńskim w 1997 roku. Odbyła staże podoktorskie w Europejskim Laboratorium Biologii Molekularnej w Heidelbergu (1998-2000) oraz w Instytucie Maxa Plancka Molekularnej Biologii Komórki i Genetyki w Dreźnie (2001-2004). Od roku 2005 kierownik Laboratorium Biologii Komórki w Międzynarodowym Instytucie Biologii Molekularnej i Komórkowej w Warszawie. Stopień doktora habilitowanego uzyskała w roku 2008, a tytuł profesora w 2013.

Jej badania z dziedziny biologii komórki dotyczą mechanizmów molekularnych, które integrują transport błonowy, w szczególności endocytozę, z wewnątrzkomórkowymi szlakami sygnalizacyjnymi. Odkryła m. in. odrębną populację wczesnych endosomów w komórce, tzw. endosomy APPL. Wraz ze swoim zespołem scharakteryzowała nowe funkcje białek endocytarnych w regulacji przekazywania sygnałów oraz transkrypcji, a także rolę endosomów jako platform sygnałowych dla receptorów czynników wzrostu i cytokin.

Współautorka ponad 40 publikacji cytowanych ponad 2100 razy. Wygłosiła kilkadziesiąt referatów i wykładów na zaproszenie na międzynarodowych konferencjach oraz w zagranicznych instytucjach naukowych. Laureatka stypendiów Austrian Science Fund (FWF), Human Frontier Science Program Organization (HFSPO) oraz L’Oreal Polska dla Kobiet i Nauki. Laureatka prestiżowych grantów zagranicznych: Wellcome Trust International Senior Research Fellowship (2006-2012) oraz Howard Hughes Medical Institute International Research Scholar (2006-2010). Kierowniczka grantów finansowanych przez Polsko-Szwajcarski Program Badawczy, Narodowe Centrum Nauki (grant MAESTRO), Unię Europejską, Towarzystwo Maxa Plancka i Ministerstwo Nauki i Szkolnictwa Wyższego. Panelistka m. in. European Research Council (LS3 starting grants), Agence Nationale de la Recherche (ANR) z Francji, Deutsche Forschungsgemeinschaft (DFG) z Niemiec. Członek Komitetu Biologii Molekularnej Komórki PAN. Promotorka 7 zakończonych przewodów doktorskich.

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Data publikacji: poniedziałek, 2. Styczeń 2017 - 08:50; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:45; osoba wprowadzająca: Maria Maja Pega

Culture of Innovation; Practitioner’s Perspective

Speaker: dr hab. Mieczyslaw (Mietek) Mazurek

Talk: Culture of Innovation; Practitioner’s Perspective

Time: 13 January 2017, 9.00 a.m.

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


mazurek

Culture of Innovation; Practitioner’s Perspective - What is true in science: “publish or perish”, in the market place translates into: “innovate or die”. Innovation is one of the key tools necessary to win in the competitive economies; innovation not only in technology, but also in processes and business models. This seminar will combine some examples and general remarks from literature regarding the subject matter with examples and observations of a researcher immersed in the creative environment of one of the most innovative global enterprises – 3M Company. A need for “systems thinking” in designing and implementing truly innovative solutions will be emphasized.

 

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Data publikacji: czwartek, 1. Grudzień 2016 - 12:53; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:45; osoba wprowadzająca: Maria Maja Pega

Rabbit Pluripotent Stem Cells: Interest and State of Art.

insremSpeaker: dr Marielle Afanassieff (Inserm, Universit Paris)

Talk: Rabbit Pluripotent Stem Cells: Interest and State of Art.

Time: 28 October 2016, 9.00 a.m.

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar

marielle

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Data publikacji: wtorek, 25. Październik 2016 - 11:36; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:46; osoba wprowadzająca: Maria Maja Pega

Linking viral immune evasion with cell proliferation - Epstein-Barr virus encoded EBNA1

Speaker: Prof. Robin Fahraeus (Inserm, Universit Paris)insrem

Talk: Linking viral immune evasion with cell proliferation - Epstein-Barr virus encoded EBNA1

Time: 7 October 2016

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


Robin Fah

Prof. Robin Fahraeus is Director of Research at the French Inserm. His team is located at the Institute Genetique Moleculair in Paris. He is member of the French Cancer Institute, the Mazaryk Cancer Institute in Brno, Czech Republic and Umea University, Sweden. He did his M.D. and PhD at the Karolinska Institute in Stockholm, Sweden in 1993. This was followed by a post doc training with Sir David Lane in Dundee, UK. He was Head of R&D at the Cyclacel Biotech Ltd before setting up his own academic research group with support from the Cancer Research UK. In 2004 he moved to France to become Research Director and work on physiological implications of mRNA translation in the p53 and the MHC class I pathways.  The team has explored viral mechanisms of immune evasion and how this is linked to alternative sources of peptides for the MHC class I pathway.  Works on the activation of p53 have shown how signaling pathways use the p53 mRNA to differentiate p53 activity following different cellular stresses. Dr Fahraeus team is currently world leading group in the studies on the source of MHC class I presented peptides. Their work contributed to understanding fundamental aspects of the processes allowing the immune system to detect self from non-self and for viral evasion of the immune system. The aim of their present research is to identify and evaluate intracellular targets for novel anti-cancer therapies. Dr Fahraeus is the author of over 80 publications in leading scientific journals, including Science, Nature, Nature Communications, PNAS, Oncogene and others. 

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Data publikacji: wtorek, 4. Październik 2016 - 08:43; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:46; osoba wprowadzająca: Maria Maja Pega

Wykład inauguracyjny 2016/2017 "Składanie pre-mRNA – molekularna gra w Scrabble" Prof. dr hab. Zofia Szweykowska-Kulińska

Speaker: Prof. dr hab. Zofii Szweykowska-Kulińska (Uniwersytet Adama Mickiewicza Poznań)UAM

Talk: Składanie pre-mRNA - molekularna gra w Scrabble

Time: 5 October 2016, 12:00

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, Aula

Category: Invited Lecture, Inauguration of the academic year


Szweykowska

Serdecznie zapraszamy na wykład Prof. dr hab. Zofii Szweykowskiej-Kulińskiej z Uniwersytetu Adama Mickiewicza w Poznaniu "Składanie pre-mRNA – molekularna gra w Scrabble". Wykład uhonoruje tegoroczną inaugurację roku akademickiego, która odbędzie 5 pażdziernika o 1200 w Auli na MWB, Instytut Biotechnologii Abrahama 58.

Tytuł magistra: 1980 biologii, UAM    Stopień doktora nauk biologicznych: 1986, UAM    Stopień doktora habilitowanego nauk biologicznych: 1995, UAM     Tytuł profesora nauk biologicznych: 2001, UAM

Postdok: stypendium Aleksandra von Humboldta: 1988-1990, Uniwersytet w Wuerzburgu, Niemcy Stypendium EMBO, 1993, CNRS, Gif-sur Yvette, Francja
Kierownik Zakładu Ekspresji Genów (od 1996) Dyrektor Instytutu Biologii Molekularnej i Biotechnologii (od 2000) na Wydziale Biologii UAM Blisko 70 prac widocznych w WoS

Tematyka: Badania dotyczą metabolizmu RNA, obecnie koncentrują się nad splicingiem i biogenezą i funkcjami mikroRNA roślin. Najważniejsze odkrycia: (1) odkryła wraz ze współpracownikami, że geny mikroRNA są długie i zawierają introny. (2) Intron lub aktywne miejsce 5’ splicingowe stymuluje biogenezę roślinnych mikroRNA obecnych w egzonie powyżej intronu, natomiast w przypadku intronowych mikroRNA jest odwrotnie: wydajny splicing i aktywne miejsce 5’ splicingowe hamują biogenezę mikroRNA . (3) Wyciszenie z pomocą sztucznego mikroRNA genu CBP80 ziemniaka zwiększa tolerancję rośliny na okresowy niedobór wody. (4) Zahamowanie krzewienia jęczmienia w stresie wysokiej temperatury jest związane z indukcją mikroRNA 444. (5) W wątrobowcu P.endiviifolia odkryto obecność kilku mikroRNA podobnych do mikroRNA glonów. Fakt ten wskazuje, że rośliny te lokują się u korzenia drzewa filogenetycznego roślin lądowych.

 

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Data publikacji: poniedziałek, 8. Sierpień 2016 - 10:04; osoba wprowadzająca: Maria Maja Pega Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:46; osoba wprowadzająca: Maria Maja Pega

Role of the complement system in cancer progression and therapy

Speaker: Marcin Okrój, PhD

Talk: Role of the complement system in cancer progression and therapy.

Time: 26 February 2016, 9.00

Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58

Category: Faculty seminar


Marcin OkrójMarcin Okrój obtained his master degree at the Intercollegiate Faculty of Biotechnology UG-AMG (Gdańsk, Poland) in 1999, then continued his scientific career at the same place as a PhD student under the supervision of prof. Jacek Bigda. He participated in two projects granted by Polish State Commitee for Scientific Research (KBN), which involved the role of cell adhesion as well as antiangiogenic compound TNP-470 in growth of rodent melanomas. Irrespectively of the main scientific activity, he was also involved in several side-projects concerning antimicrobial peptides. In 2003, as a beneficient of Marie-Curie Program, he obtained 6-month training at the Free University of Amsterdam (Amsterdam, The Netherlands) and finally defended his PhD thesis in 2004.

After working for 1 year at Pasteur Institute (Paris, France), Dr Okrój joined the team of prof. Anna Blom at Lund University (Malmö, Sweden), which was engaged into innate immunity and especially the complement system. In 2010 he obtained support from Swedish Research Council (Vetenskapsrådet) and initiated an independent line of research focused on the role of complement in tumor progression, identification of novel complement inhibitors and design of new immunological methods.

Currently Dr Okrój is a principal investigator within two projects funded by National Science Centre (NCN, Poland): i) ¨Role of the complement system in tumorigenesis and therapeutic approaches.¨ (Sonata Bis) and ii) ¨Functional characteristics and therapeutic potential of gain-of-function mutations in complement C2 protein.¨ (Harmonia). He is the author of 30 peer-reviewed publications and named as inventor in one patent. Dr Okrój is a member of International Complement Society, European Complement Network and research program Biomarkers in Cancer Medicine (BioCare).

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Data publikacji: czwartek, 4. luty 2016 - 08:30; osoba wprowadzająca: Katarzyna Maczyszyn Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:47; osoba wprowadzająca: Katarzyna Maczyszyn

Filaggrin utilize actins to regulate keratinocyte differentiation and cornification during epidermal barrier formation - Danuta Gutowska-Owsiak

Speaker: Danuta Gutowska-Owsiak, PhD

Talk: Filaggrin utilize actins to regulate keratinocyte differentiation and cornification during epidermal barrier formation

Time: 22 January 2016, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar

Załącznik Rozmiar
Danuta Gutowska-Owsiak - biographical note 76.18 KB
Abstract 102.42 KB
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Data publikacji: poniedziałek, 1. luty 2016 - 12:06; osoba wprowadzająca: Katarzyna Maczyszyn Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:47; osoba wprowadzająca: Katarzyna Maczyszyn

Mikhail I. Zarayskiy (First Pavlov State Medical University of Saint Petersburg, Russia)

Speaker: Prof. Mikhail I. Zarayskiy (Clinical Laboratory, First Pavlov State Medical University of Saint Petersburg, Russia)

Talk: The modern concept of the DNA structure and regulation

Time: 23 October 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar

 


Mikhail I. ZarayskiyMikhail I. Zarayskyi is professor of Clinical Laboratory at the First Pavlov State Medical University of Saint Petersburg in Russia. Hi is a group leader ‘Molecular Diagnostics in Oncology’. He graduated in medicine in 1984 at Saint-Petersburg Medical Institute of Hygiene and Sanitation. Then he obtained PhD degree for research on ‘The role of HLA markers in prognosis of multiple myeloma’ (1985) and ‘Molecular aspects of the main complications in hemopoietic stem cell transplantation’ (1995). His research interests focus primarily on molecular and genetic aspects of oncogenesis (telomerase activity, mutagenesis in the apoptotic genes (p53, p21, BCL-2), intracellular signaling (Jak, HOX, STAT), allogenic bone marrow transplantation, renal transplantation and micro-RNA control of tumor cells. He is currently a member of the European Dialysis and Transplant Association.

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Data publikacji: piątek, 16. Październik 2015 - 08:25; osoba wprowadzająca: Anna Gwizdek-Wiśniewska Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:48; osoba wprowadzająca: Anna Gwizdek-Wiśniewska

Luis M. Schang (Li Ka Shing Institute of Virology, University of Alberta, Canada)

Speaker: Dr. Luis M. Schang (Li Ka Shing Institute of Virology, University of Alberta, Canada)

Talk: Chromatin silencing as an antiviral innate immune response

Time: Friday, 2015-10-16, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar

 


Luis M. Schang, biographical note

Prof. Luis M. Schang

Dr. Luis M. Schang is a Professor at the Department of Biochemistry of the Faculty of Medicine and Dentistry of the University of Alberta, cross-appointed to the Department of Medical Microbiology and Immunology. He is also a founding member of the Li Ka Shing Institute of Virology and a founding member and president of ProPhysis, Ltd. He is the director of the MD with Special Training in Research (MD-STIR) program. Dr. Schang is an active member of the International Society for Antiviral Research (ISAR) and the International Herpesvirus Workshop (IHW). He is a section editor for PLOS ONE, a member of the editorial boards of two of the official publications of the American Society for Microbiology (ASM), the Journal of Virology, and Antimicrobial Agents and Chemotherapy, and an associate editor of Virology Journal. He also reviews papers for a number of high-impact scientific publications. He is a permanent or ad hoc member of grant review panels of the Canadian Institutes of Health Research (CIHR), the National Institute of Health, USA (NIH), and a number of other International granting agencies. His research interests are centered in chemical virology, the use of small chemical probes to interrogate virus-infected cells to identify factors required for viral replication and leads toward the development of new antiviral drugs. His group discovered the first lipid-targeting antiviral compounds and spearheaded the study of chromatin dynamics and epigenetics in lytic HSV infections, playing a critical role in our current understanding of the roles of chromatin as an antiviral innate cellular defense. Previously, Dr. Schang had identified the roles of the cellular cyclin-dependent kinases in viral replication and pathogenesis, and championed the use of inhibitors of cellular protein kinases against virus-induced cancers. He has been continuously funded by Canadian and American sources since 2001. Dr. Schang has published 60 original research, review or editorial articles or book chapters and holds four issued patents on novel antivirals.

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Data publikacji: poniedziałek, 12. Październik 2015 - 15:17; osoba wprowadzająca: Anna Gwizdek-Wiśniewska Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:48; osoba wprowadzająca: Anna Gwizdek-Wiśniewska

Paul Williams (Centre for Biomolecular Sciences, University of Nottingham, United Kingdom)

Speaker: Paul Williams (Centre for Biomolecular Sciences, University of Nottingham, United Kingdom)CBS

Talk: The art of antibacterial warfare – deception through interference with quorum sensing–mediated communication

Time: Friday, 3rd July 2015, 09:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Paul Williams, biographical note

Williams

Paul Williams is Professor of Molecular Microbiology in the School of Life Sciences, Faculty of Medicine and Health Sciences at the University of Nottingham U.K. He graduated in pharmacy in 1979 prior to undertaking a Ph.D in microbiology (1984). In 1996 he was appointed to the Directorship of the Institute of Infection, Immunity and Inflammation until 2008 when he became Head of the School of Molecular Medical Sciences, University of Nottingham.  His research interests focus primarily on the regulation of gene expression in bacteria through cell-cell communication (quorum sensing) and the development of novel antibacterial agents and bacterial attachment resistant polymers. He has published around 300 research papers, reviews and book chapters and patents. For his quorum sensing research he was awarded the Royal Pharmaceutical Society of Great Britain Conference Science Medal (1992), Pfizer prize in Pharmaceutical Sciences (1994) and the Society for General Microbiology Colworth Prize Lecture in 2007.  Prof. Williams has served on the editorial/advisory boards of Environmental Microbiology, Journal of Bacteriology Microbiology, FEMS Microbiology Letters, Biofilms, International Journal of Medical Microbiology and Molecular Microbiology. He has also been a member of the Biotechnology and Biological Sciences Research Council U.K. (Plants and Microbes Committee), the Medical Research Council (MRC) U.K. Advisory Board, the MRC College of Experts, the Infection Group of the Society for General Microbiology and was a specialist advisor for the UK RAE2008 research selectivity exercise.  He is currently a member of the MRC Infection and Immunity board, a member of the EU Joint Programming Initiative in Antimicrobial Resistance and is a Welcome Trust Senior Investigator.

 

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Data publikacji: czwartek, 27. Sierpień 2015 - 08:30; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:48; osoba wprowadzająca: Elżbieta Moroz

Pierre Savatier (INSERM U846 Stem Cell and Brain Research Institute, France)

Speaker: Pierre Savatier (INSERM U846 Stem Cell and Brain Research Institute, France)INSERM

Talk: Understanding and manipulating pluripotent stem cells: toward applications in basic biology, biotechnology and medicine

Time: Friday, 25th November 2016, 09:00 – 10:00

Venue: Faculty Seminar

Time: Thursday, 2nd July 2015, 09:00 – 10:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Pierre Savatier, biographical note

Pierre SavatierDr. Pierre Savatier obtained his PhD in biology at the University of Lyon, France, working on genome evolution in primates. He was a postdoctoral fellow at Oxford University in the late 80’s, working on mouse early embryo development and pluripotent stem cells. Then he joined the Ecole Normale Supérieure in Lyon to start his own team, working on cell cycle regulation both in mouse embryonic stem cells and neural precursors of the developing cortex. In 2004, he joined the National Institute for Health and Medical Research (INSERM) in Lyon, and participated in the creation of the Stem Cell and Brain Research Institute (www.sbri.fr), where he now heads the team “Pluripotent stem cells in mammals”. His current research interests include the regulation of pluripotency in the early embryo of rabbits, macaque monkey and human, and the generation of somatic and germline chimeras in rabbits and non-human primates with engineered embryonic and induced pluripotent stem cells. Pierre Savatier is a member of DEVweCAN, a cluster of Excellence dedicated to development and cancer research, and CORTEX a cluster of Excellence dedicated to the study of brain development and repair.

 

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Data publikacji: czwartek, 27. Sierpień 2015 - 08:21; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:49; osoba wprowadzająca: Elżbieta Moroz

Ezio Ricca (University of Naples Federico II, Italy)

Speaker: Ezio Ricca (University of Cambridge, United Kingdom)University of Naples

Talk: Microbiology and Biotechnological Applications of Spore Formers

Time: Friday, 3rd July 2015, 10:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Ezio Ricca, biographical note

Ezio RiccaEzio Ricca is a professor of Microbiology of the Federico II University of Naples (Italy). As a student of the University of Naples, he worked for his Thesis at the International Institute of Genetic and Biophysics (IIGB) of Naples under the supervision of Prof. M. De Felice on the molecular characterization of Escherichia coli mutants altered in the biosynthesis of branched-chains amino acids. After that Ezio spent more than two years as a post-doctoral fellow in the laboratory of Prof. J.M. Calvo at the Department of Biochemistry and Cell Biology of the Cornell University, Ithaca, NY (US). At Cornell Ezio worked on the transcriptional regulation of the ilvIH operon of Escherichia coli and Salmonella typhimurium identifying and characterizing Lrp, a global regulator of metabolism in enterobacteria. From 1990 Ezio became interested in gram-positive spore forming bacteria and spent two years in the laboratory of Prof. R. Losick at the Department of Cellular and Developmental Biology of the Harvard University, Cambridge, MA (US). At Harvard Ezio worked on the activation of sigmaK, a sporulation-specific sigma factor of the RNA polymerase, on the characterization of the sporulation gene spoVM and on the identification of CotG, an abundant component of the spore surface. Since Ezio return to Italy at the Federico II University of Naples, his research interests have been focused on the study of the bacterial spore surface and on the use of spores as a biotechnological tool. In particular, Ezio developed the use of the spore as a mucosal delivery system and as a probiotic agent. More recently, Ezio became also interested in the study of the interactions between commensal bacteria and intestinal cells and in the effects of bacteria and bacterial molecules on the composition of the gut microbiota. Since 2003 Ezio Ricca is in the Editorial board of FEMS Microbiol Lett, and is in the Organizing Committee of the “European Spores Conference” (Bratislava, Slovakia, 2004 and 2006; Napoli, Italy, 2008; Cortona, Italy, 2010; Egham, UK, 2012 and 2014).

 

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Data publikacji: czwartek, 27. Sierpień 2015 - 08:10; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:49; osoba wprowadzająca: Elżbieta Moroz

Takashi Kuwana (KAWA.SKA Sp. z o.o., Poland)

Speaker: Takashi Kuwana (KAWA.SKA Sp. z o.o., Poland)KAWA.SKA

Talk: Microsurgery techniques in biology

Time: Friday, 3rd July 2015, 11:30

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Takashi Kuwana, biographical note

Takashi KuwanaPh.D. (1981)       Graduate School of Medical Science, Kumamoto University, Japan

1981 to 1987       Assistant Lecturer, Dept. of Anatomy, Kumamoto University Medical School, Japan

1987 to 1991       Lecturer, Dept. of Anatomy, Kumamoto University Medical School

1989 to 1990       International Exchange Researcher between Japan and Poland

1991 to 2003       Head, Pathology Section, National Institute for Minamata Disease, Japan

1998 to 2004       Professor, Faculty of Life Science, Kumamoto Univ., Japan

2003 to 2009       Chief, Biological Resource Laboratory, Laboratory for Intellectual Fundamentals for Environmental Studies (LIFES), National Institute for Environmental Studies (NIES), Japan

2009 to 2011       Director, LIFES, NIES, Japan

2011 to 2014       General Director, International Institute of Avian Conservation Science, Management of Nature Conservation, Department of the President’s Affairs, United Arab Emirates

2011 to present   Professor, Institute of Advanced Technology, Kinki University, Japan

2015 to present   Scientific Consultant, KAWA.SKA Sp. z o.o., Poland

 

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Data publikacji: czwartek, 27. Sierpień 2015 - 07:49; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:50; osoba wprowadzająca: Elżbieta Moroz

Jarosław Korczyński (KAWA.SKA Sp. z o.o., Poland)

Speaker: Jarosław Korczyński (KAWA.SKA Sp. z o.o., Poland)KAWA.SKA

Talk: To see invisible. Imaging techniques in fluorescence microscopy

Time: Friday, 3rd July 2015, 13:15

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Jarosław Korczyński, biographical note

Jarosław KorczyńskiSince childhood I was interested in biology and generally nature. I followed my interests during my education process and finally graduated biology with honors at Jagiellonian University in Cracow, Poland. There, for the first time, I have become acquainted with the fascinating world of microscopy experiments. Continuing my fascination with biology I began PhD studies at the Nencki Institute of Experimental Biology in Warsaw, Poland, where I investigated signaling pathways which regulate actin cytoskeleton dynamics in glioma C6 cells and astrocytes, using both biochemical and confocal microscopy techniques. There I met with a different type of fluorescent experiments like 3D visualization, FRET and FRAP techniques, STED microscopy, Calcium measurement and live cell imaging. Now, since July of this year, I’m working as an application specialist in KAWA.SKA Company – distributor of microscopy equipment in Poland.

 

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Data publikacji: czwartek, 27. Sierpień 2015 - 07:30; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:50; osoba wprowadzająca: Elżbieta Moroz

Adam Jagiełło Rusiłowski (University of Gdańsk, Poland)

Speaker: Adam Jagiełło Rusiłowski (University of Gdańsk, Poland)University of Gdansk

Workshop: Principles of intercultural cooperation for research teams

Time: Thursday, 2nd July 2015, 11:30

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Adam Jagiełło Rusiłowski, biographical note

Adam Jagiełło-RusiłowskiAdam Jagiello-Rusilowski – is an educator and social entrepreneur. He holds MA in English Literature and PhD in Educational Psychology from University of Gdansk. He studied Drama in Education at University of Northern Iowa, Community Leadership at Picker Centre, Columbia University and Social Economics at INSEAD Business School (Fontainableau).  He ran 3 youth NGOs, was Ford and Ashoka’s  fellow, worked as an expert for Soros Foundations in Eastern Europe, European Cultural Foundation in Amsterdam and UNWRA in Gaza Strip.  His original idea of self-sustainable system of training young actors as youth workers using drama to promote social and civic competences among the socially excluded (working class) children was scaled through various programs in South Eastern Europe, Russia, Peru, Uzbekistan and Palestine (Gaza Strip).

Currently he works as Dean of Development and  International Programs at Faculty of Social Sciences, University of Gdansk. As a researcher he is interested in Lisbon Key Competences in Education in particular looking at activities promoting pro-social and entrepreneurial (innovation) attitudes in young Europeans and Arabs.

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Data publikacji: środa, 26. Sierpień 2015 - 14:51; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:50; osoba wprowadzająca: Elżbieta Moroz

Florian Hollfelder (University of Cambridge, United Kingdom)

Speaker: Florian Hollfelder (University of Cambridge, United Kingdom)University of Cambridge

Talk: Rules and Tools for Efficient Enzyme Evolution, Recruitment and Discovery

Time: Wednesday, 1st July 2015, 09:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Florian Hollfelder, biographical note

Florian HollfelderFlorian Hollfelder was educated at the Technical University of Berlin (Diplom-Chemiker) and Cambridge University (MPhil). After a formative stay at Stanford (with Dan Herschlag) on free-energy relationships in enzymes, he joined Tony Kirby’s group at the Chemistry Department of Cambridge University working on enzyme models and physical-organic chemistry. During his PhD he also collaborated with Dan Tawfik (on the mechanism and evaluation of model enzymes such as catalytic antibodies). His postdoctoral work at Harvard Medical School (with Chris T. Walsh) was concerned with the biosynthesis and action of the natural antibiotic microcin B17. In 2001 he returned to Cambridge to start his own research group in the Biochemistry Department. The group’s research centers around quantitative and mechanistic questions at the chemistry/biology interface, involving low- and high-throughput approaches. Florian is Director of Studies and Graduate Mentor at Trinity Hall. He was coordinator of several EU-funded trans-national collaborative initiatives, e.g. the EU New and Emerging Science and Technology project MiFem on biological experiments in microdroplet reactors, and Marie-Curie networks on directed evolution of functional proteins (ENDIRPRO, ENEFP), on protein-protein interactions (ProSA) and on biological phosphates (PhosChemRec).

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Data publikacji: środa, 26. Sierpień 2015 - 14:41; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:51; osoba wprowadzająca: Elżbieta Moroz

Rafael Giraldo (Centro de Investigaciones Biológicas – CSIC, Madrid, Spain)

Speaker: Rafael Giraldo (Centro de Investigaciones Biológicas – CSIC, Madrid, Spain)CSIC

Talk: Synthetic Biology: News ways and tools to engineer biological systems

Time: Thursday, 2nd July 2015, 10:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Rafael Giraldo, biographical note

Rafael GiraldoRafael got a Ph. D. Biol. Sci. in 1991 (Complutense U., Madrid) on the genetics and biochemistry of plasmid DNA replication initiation, under the supervision of R. Díaz-Orejas (CIB-CSIC). Then, he spent a postdoctoral (1992-94) in the group of D. Rhodes at the MRC Laboratory of Molecular Biology (Cambridge, UK), where he studied the role of the yeast Rap1 protein in packing telomeric dsDNA, which led to the crystal structure of the first telomeric nucleoprotein complex. Rafael also found that Rap1 promoted the assembly of parallel DNA quadruplexes by the G-rich strand of yeast telomeres, an early example of a protein chaperoning a DNA structure. Back to CIB-CSIC, first as a postdoctoral (1995-1999) and since then as staff scientist, his main focus was on how sequence-specific DNA binding elicits conformational changes in the winged-helix (WH) domains of plasmid-encoded bacterial replication (Rep) proteins. Besides this, he studied the assembly of yeast ORC initiator. In 2007, Rafael found the way to tailor WH domains to become DNA-modulated amyloidogenic devices, having recently developed synthetic prion-like modules recapitulating essential features of mammalian amyloid proteinopathies (e.g.: toxicity, modulation by chaperones of conformational strains), albeit confined to a bio-safe bacterial host. Since 2010, he is a CSIC Research Professor and a member of Academia Europaea. In 2015, he has been elected as Vice-President of the Spanish Society for Microbiology (SEM).

More info:       http://www.cib.csic.es/en/grupo.php?idgrupo=61

http://www.researchgate.net/profile/Rafael_Giraldo

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Data publikacji: środa, 26. Sierpień 2015 - 14:31; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:51; osoba wprowadzająca: Elżbieta Moroz

Grzegorz Gacek (KAWA.SKA Sp. z o.o., Poland)

Speaker: Grzegorz Gacek (KAWA.SKA Sp. z o.o., Poland)KAWA.SKA

Talk: Advanced Laser Microdissection Systems

Time: Friday, 3rd July 2015, 12:00

Workshop:  Stereoscope microscopy techniques

Time: Friday, 3rd July 2015, 09:30 – 11:00 (gr. A) and 15:00 – 16:30 (gr. C)

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Grzegorz Gacek, biographical note

Biologist, widefield microscopy, TIRF microscopy, laser microdissection and stereomicroscopy specialist. Application specialist in KAWA.SKA Sp. z o.o. the distributor of Leica Microsystems in Poland.

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Data publikacji: środa, 26. Sierpień 2015 - 14:24; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:51; osoba wprowadzająca: Elżbieta Moroz

Filip Dutka (Institute of Physical Chemistry, Polish Academy of Sciences, Poland)

Speaker: Filip Dutka (Institute of Physical Chemistry, Polish Academy of Sciences, Poland)IchF

Talk: Growth of microorganisms in microfluidic devices

Time: Wednesday, 1st July 2015, 10:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Filip Dutka, biographical note

Filip DutkaMy scientific field of interest is soft condensed matter and application of microfluidics in  the fields of microbiology and medicine. During my master and doctoral studies at the Faculty of Physics, University of Warsaw (Poland) I was looking into mathematical description of the liquid-gas fluid interfaces on nanoscale and phenomena such as wetting and morphological phase transitions. I continued research on nanodroplet shapes on my Post Doc in the Max-Planc-Institute if Intelligent Systems in Stuttgart (Germany). Using methods of statistical physics I explained Gibbs’ criterion on nanoscale.

Coming back to Poland range of my scientific research expanded by the experimental methods in the discipline of microfluidics. In the Microfluidics and Complex Fluids Research Group, Institute of Physical Chemistry, Polish Academy of Sciences (Poland) we design and fabricate microfluidic devices in which droplets can form separate microbioreactors. In our Homing Plus project granted by the Foundation for Polish Science we constructed device in which full automated culturing of microorganisms and their online growth dynamics monitoring is possible.

 

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Data publikacji: środa, 26. Sierpień 2015 - 13:56; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:52; osoba wprowadzająca: Elżbieta Moroz

Charles Cantor (Sequenom Inc., San Diego, California, USA)

Speaker: Charles Cantor (Sequenom Inc., San Diego, California, USA)Sequenom

Talk: The future of DNA diagnostics

Time: Friday, 3rd of July 2015, 12:30

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Charles Cantor, biographical note

Charles CantorDr. Charles Cantor is a founder, and retired Chief Scientific Officer at SEQUENOM, Inc., which is a genetics discovery company with tools, information and strategies for determining the medical impact of genes and genetic variations. Dr. Cantor consults for a number of biotech companies including SEQUENOM, Agena and Retrotope. He is also the founder of SelectX Pharmaceuticals, a drug discovery company, Retrotope, an anti-aging company, and DiThera, a biotherapeutic company.

Dr. Cantor is professor emeritus of Biomedical Engineering and of Pharmacology and was the director of the Center for Advanced Biotechnology at Boston University. He is currently adjunct professor of Bioengineering at UC San Diego, adjunct professor of Molecular Biology at the Scripps Institute for Research, distinguished adjunct professor of Physiology and Biophysics at UC Irvine and adjunct professor at the Moscow institute of Physics and Technology. Prior to this, Dr. Cantor held positions in Chemistry and then in Genetics and Development at Columbia University and in Molecular Biology at the University of California at Berkeley. Cantor was educated in chemistry at Columbia College (AB) and at the University of California Berkeley (PhD).

Dr. Cantor has been granted more than 60 US patents and, with Paul Schimmel, wrote a three-volume textbook on biophysical chemistry. He also coauthored the first textbook on Genomics titled 'The Science and Technology of the Human Genome Project'. In addition, he has published more than 450 peerreviewed articles, and is a member of the U.S. National Academy of Sciences.

His major scientific accomplishments include the development of pulsed field electrophoresis, immuno PCR, affinity capture electrophoresis, the earliest uses of FRET to characterize distances in protein complexes and nucleic acids, the standard methods for assaying and purifying microtubule protein, various applications of nucleic acid mass spectrometry, and methods for noninvasive prenatal diagnostics. He is also considered to be one of the founders of the new field of synthetic biology.

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Data publikacji: środa, 26. Sierpień 2015 - 13:34; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:52; osoba wprowadzająca: Elżbieta Moroz

Zbigniew Brzózka (Warsaw University of Technology, Poland)

Speaker: Zbigniew Brzózka (Warsaw University of Technology, Poland)Warsaw University of Technology

Talk: Lab-on-a-Chip devices for long-term cell culture and anticancer drug activity evaluation

Time: Wednesday, 1st of July 2015, 11:30

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Zbigniew Brzózka, biographical note

Zbigniew BrzózkaProf. Zbigniew Brzózka obtained his Ph.D. in analytical chemistry at the Warsaw University of Technology, studying mechanisms of transition metal cations by carboxylic acids. He was a postdoctoral fellow at ETH Zurich in the middle 80’s, working on new membrane selective electrodes in Prof. W. Simon’s group supported by the Swiss National Science Fundation and by Orion Research, Inc. Then he came back to Department of Analytical Chemistry of Warsaw University of Technology and finished his Dr.Sc. in chemical sciences.

Within 1991 – 1993, he was working in postdoc position in Prof. D.N. Reinhoudt’s group (University of Twente), supported by the Royal Dutch Science Foundations (NWO, STW), by Priva and Sentron, Inc. He was involved in a number of projects on molecular recognition based on supramolecular chemistry and its application to chemical sensors (chemically modified field-effect transistors, membrane ion-selective electrodes, fibre-optic sensors) suitable for monitoring in clinical diagnostic and environmental protection. One of the most interesting topic was anion recognition (in nature, the selective complexation of anions takes place by hydrogen bonds) and his research was focused on a novel type of neutral anion receptors consisting of a combination of a Lewis acidic center and fragments involving hydrogen bonds.

Since 1998, he is tenured professor of bioanalytics in Faculty of Chemistry, Institute of Biotechnology, Department of Microbioanalytics and now heads the “Miniaturized analytical systems” team. His current research interests focus on miniaturized analytical systems (Lab-on-a-Chip) for monitoring of bioanalytes. Emphasis is now also being laid on the applications of polymer microfabrication technologies to microchemical analysis, i.e. the integrated microchips with optical and electrochemical detection principles dedicated to early diagnostics of genetic diseases as a novel approach to reliably diagnose patients, and protect them from mistaken diagnoses and disorder progress. Another field of interest of the partners will be the development of polymeric chips for human cell culture in unique, in vivo-mimicking microenvironment where studies of cellular growth and responses to external factors are conducted for drug screening and toxicology applications.

Zbigniew Brzózka has received Professor Subvention of The Foundation for Polish Science (2003-2006) and Wiktor Kemula Medal (Honour Award of Polish Society of Chemistry) (in 2010). Since September 2008, he is Dean of Faculty of Chemistry, Warsaw University of Technology.

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Data publikacji: środa, 26. Sierpień 2015 - 13:05; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:52; osoba wprowadzająca: Elżbieta Moroz

Joanna Bagniewska (University of Reading, United Kingdom)

Speaker: Joanna Bagniewska (University of Reading, United Kingdom)University of Reading

Workshop: Science Communication

Time: Friday, 3rd of July 2015, 15:00

Venue: Biotechnology Summer School 2015, Kadyny Folwark Hotel&SPA

Category: Invited lectures during Biotechnology Summer School


Joanna Bagniewska, biographical note

Joanna BagniewskaDr Joanna Bagniewska is a zoologist specializing in behavioral ecology and invasive species research.  She obtained her MSc and doctorate from Oxford University’s Zoology Department. Thus far she conducted research in five countries and visited over 40, having studied foxes and jackals in South Africa, wombats and wallabies in Australia, mole-rats in the USA and mink and bees in the UK. Currently she works as a teaching fellow for the School of Biological Sciences at the University of Reading.

Joanna is passionate about science communication and is constantly engaged in a number of outreach activities. In 2014 she won FameLab Poland, a science communication competition for researchers, and went on to receive the Alumni Award in the international finals of the event. For the last two years she has co-organised the popular science conference “Science. Polish Perspectives”; more recently she has taken part in endeavours such as the theatrical Science Slam, science stand-up comedy for Bright Club Oxford and Museums Show Off, and the school-oriented I’m a Scientist – Get me out of here! She also described her research during a talk at TEDxWarsaw. Joanna regularly writes for Gazeta Wyborcza and Focus, and runs a blog on INNPoland.pl. In her free time (or what is left of it!) she acts as the principal ambassador for Oxford in The Kings Foundation, a mentoring scheme for university applicants.

 

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Data publikacji: środa, 26. Sierpień 2015 - 12:55; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:52; osoba wprowadzająca: Elżbieta Moroz

Zbigniew Arent DVM, PhD, MRCVS

Speaker: Zbigniew Arent DVM, PhD, MRCVSMRCVS logo

Talk: Aspects of immunity in bovine leptospirosis

Time: 12 June, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar


Zbigniew Arent, biographical note

Zbigniew Arent photoQualified as veterinary surgeon from the Faculty of Veterinary Medicine  in Olsztyn in 1993. Following his graduation he has spent much of his career in infectious disease  science and research. He completed a PhD in veterinary microbiology in 2000 for studies on improvement of  diagnostic methods  of ram epididymitis caused by Brucella ovis.  During his postdoctoral position he started his interests on leptospirosis. In 2007 he moved to Northern Ireland where he joined OIE Leptospirosis Reference Laboratory in AFBI, one of the essential in leptospirosis laboratories in Europe. The mission of his work is to improve the recognition and control of leptospirosis of animals. He is interested in host responses to infection as it relate to serological diagnosis, vaccinal immunity in domestic animals, molecular tools used to improve diagnosis and strains typing methods.

 

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Data publikacji: piątek, 15. Maj 2015 - 08:56; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:53; osoba wprowadzająca: Elżbieta Moroz

Innovations in environmental friendly productions of lipids and proteins for industry

MOBI4Health logoSpeakers: Prof. Ivo Feussner, University of Gottingen; Prof. Roman Zubarev, Karolinska Institute; Dr Andreas Marquardt, University of Konstanz; Dr Michal Sharon, Weizmann Institute of Science; Dr Piotr Stefanowicz, University of Wroclaw; Cyrus Papan, Sciex;

Topic: Innovations in environmental friendly productions of lipids and proteins for industry

Time: 18 March 2015

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Open lecture session


Open session organized within the MOBI4Health project during the workshop focusing on application of mass spectrometry in biological science. The main subject of the workshop is “Innovations in environmental friendly productions of lipids and proteins for industry”.

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Data publikacji: wtorek, 7. Kwiecień 2015 - 15:16; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:54; osoba wprowadzająca: Elżbieta Moroz

Frank Graage (Steinbeis-Forschungszentrum Technologie-Management Nordost, Germany)

Speaker: Frank Graage (Steinbeis-Forschungszentrum Technologie-Management Nordost, Germany)Steinbeis logo

Talk: Motivation to get engaged with Horizon 2020 for scientists. Why and when participate - a realistic view to make the decision

Time: 29 May, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Lecture


Frank Graage, biographical note

Frank Graage (Steinbeis Team Northeast) - Expert on EU proposal preparation and management in Life Sciences, EU-Evaluator

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Data publikacji: piątek, 27. luty 2015 - 10:14; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:53; osoba wprowadzająca: Elżbieta Moroz

Monika Słomińska-Wojewódzka (University of Gdańsk, Poland)

Speaker: Dr Monika Słomińska-Wojewódzka (University of Gdańsk, Poland)

Topic: Substrate specificity of the endoplasmic reticulum chaperone proteins EDEM1 and EDEM2, and their role in the intracellular transport of ricin [abstract in PDF]

Time: 13 March, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited seminar


Monika Słomińska-Wojewódzka, biographical note

Monika Słomińska-Wojewódzka studied Biotechnology at the Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk. She obtained her PhD in molecular biology  at the Faculty of Biology, Geography and Oceanology, University of Gdańsk in 2003 working in the field of bacteriophage genetics. In 2003-2005 she worked as a postdoctoral fellow at the Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. Her scientific interests focused on the intracellular transport of ricin, a protein toxin. This fellowship was financed by the European Molecular Biology Organisation (EMBO long-term fellowship). Currently, she works at the Laboratory of Cell Signaling at the Department of Molecular Biology, University of Gdańsk. The main objectives of her research interests involve investigation of the role of endoplasmic reticulum (ER) chaperone proteins and ER translocons in protein transport to the cytosol and detailed analysis of ricin cytotoxic effect on different cancer cell lines.

 

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Data publikacji: piątek, 20. luty 2015 - 09:09; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:54; osoba wprowadzająca: Elżbieta Moroz

Niki Karachaliou (Catalan Institute of Oncology, Badalona, Barcelona, Spain)

Speaker: Dr. Niki Karachaliou (Catalan Institute of Oncology (ICO) – Badalona, Barcelona, Spain)

Talk: Integrated research in STAT3 in cancer stem cells. Early adaptive resistance to EGFR inhibition in EGFR mutant Non-Small-Cell-Lung-Cancer

Time: 27 March, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar


Niki Karachaliou, biographical note

Niki Karachaliou photoDr Niki Karachaliou is a medical oncologist and member of the Translational Research Unit of the Instituto Oncológico Dr Rosell in Barcelona. She completed her graduate studies at the University of Athens Medical School (1994-2002) and achieved a score of 9 (maximum possible 10). She completed a three-year residency in internal medicine, including six months in hematology, and a second three-year residency in medical oncology at the University Hospital of Heraklion, Crete, Greece (2005-2011). In 2012, she was accepted as a translational research fellow under the mentorship of world-renowned medical oncologist and translational researcher Dr Rafael Rosell in Barcelona, Spain.

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Data publikacji: czwartek, 19. luty 2015 - 12:50; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:54; osoba wprowadzająca: Elżbieta Moroz

Peter Gimeson (Malvern Instruments Ltd.)

Speaker: Peter Gimeson (Malvern Instruments Ltd.)

Talk: Managing heat and disorder, calorimetric assays in life sciences [abstract, PDF]

Time: 6 March, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Seminar


Peter Gimeson, biographical note

Peter joined Malvern Instruments Ltd 2014 in connection to the acquisition of MicroCal from GE Healthcare. Prior that, Peter worked at GE healthcare, Life sciences as senior application specialist for microcalorimetry covering Europe, Middle East and Africa. The function allows him to interact with users on a daily basis regarding all aspects of instrumentation, assay developments and data analysis in Isothermal Titration Calorimetry and Differential Scanning Calorimetry. He is based in Uppsala, Sweden. The role includes working closely with MicroCal R&D, service and Instrument user groups in both academic and industrial environments. A large part of his work is conducting training sessions, support visits and data analysis consultancy on/off site. Peter holds a Ba in Chemistry, Umeå University, Sweden

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Data publikacji: piątek, 13. luty 2015 - 15:02; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:55; osoba wprowadzająca: Elżbieta Moroz

Tim Maisch (University Hospital Regensburg, Germany)

Speaker: Dr. Tim Maisch, PhD (University Hospital Regensburg, Germany)

Talk: A new trend against Superbugs: The Photodynamic Principle [abstract in PDF]

Time: 20 February, 2015, 9:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited Lecture


Tim Maisch, biographical note

Tim Maisch studied Biology at the University of Erlangen-Nuremberg, Germany. He gained extensive laboratory experience working under the guidance of Prof. Dr. M. Mach at the Institute of Clinical and Molecular Virology, Univ. of Erlangen-Nuremberg. In 1997 he received his diploma and achieved his Ph.D. with a thesis titled "Upregulation of protein expression on endothelial cells infected with human cytomegalovirus” in 2001. Since 2002, he has been working as postdoctoral fellow at the Department of Dermatology, University Hospital of Regensburg on photodynamic inactivation of multi-resistant bacteria. He gained his Postdoctoral Habilitation in 2009 (venia legendi). Since 2008, he is the head of the laboratory of the Department of Dermatology. Currently he is the laboratory head of the Antimicrobial Photodynamic and Cold Plasma Research Unit at the Department of Dermatology, University Hospital Regensburg.

 

 

Main objectives of his research interests are:

  • Investigation of the role of singlet oxygen and oxygen consumption in photodynamic inactivation of bacteria as well as the detection of singlet oxygen directly by its luminescence
  • Development of new photosensitizers for the photodynamic treatment of bacterial and fungal infections in cooperation with the Department of Organic Chemistry, University of Regensburg
  • Preclinical evaluation of new photosensitizers for topical application in dentistry and dermatology
  • Development of photodynamic active surfaces to prevent contamination with microorganisms
  • Application of cold atmospheric plasma against microorganisms in cooperation with the Max-Planck-Institute for Extraterrestic Physics (MPE)

Research awards

  • 3/2012 Award for best poster presentation during the 39. ADF-Annual Conference, Marburg (01.03.-03.03.2012) mit dem „Photodynamic killing of enterohaemorrhagic Escherichia coli (EHEC) for the first time using TMPyP”
  • 3/2008 Arnold-Rikli-Award to support photo-biological research interests of light in relation to human medicine in the future
  • 11/2006 PDT-2006 Award to support the research interest in photodynamic therapy and fluorescence diagnosis of skin diseases
  • 3/2006 Award for best poster presentation during the 33. ADF-Annual Conference, Aachen (23.03. – 25.03.2006) “Investigation of photodynamic inactivation of bacteria using the detection of singlet oxygen luminescence”

Affiliations

American Society for Microbiology (ASM)

European Society for Photobiology (ESP)

Until now he has 50 publications in peer-reviewed journals and he is associate editor of the journal Photochemistry & Photobiology Sciences and a member of the editorial board of Anti-Infective Agents in Medicinal Chemistry.

 

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Data publikacji: środa, 11. luty 2015 - 14:05; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:55; osoba wprowadzająca: Elżbieta Moroz

Włodzimierz Krzyżosiak (Institute of Bioorganic Chemistry of Polish Academy of Sciences)

Speaker: prof. dr hab. czł. koresp. PAN Włodzimierz Krzyżosiak (Instytut Biochemii Organicznej PAN)

Talk: Patologiczne ekspansje mikrosatelitów – rola RNA w patogenezie i terapii

Time: December 2, 2014, 12:00

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24, lecture hall B

Category: Invited lecture during Academy Open Ceremony at IFB


Włodzimierz Krzyżosiak, notka biograficzna

Profesor Włodzimierz Krzyżosiak jest kierownikiem Zakładu Biomedycyny Molekularnej w Instytucie Chemii Bioorganicznej PAN w Poznaniu. Jego droga naukowa wiodła od chemii strukturalnej kwasów nukleinowych, poprzez biologię i genetykę molekularną oraz genetykę nowotworów do medycyny molekularnej. Przez pięć lat pracował zagranicą w placówkach badawczych Anglii, Francji, USA i Japonii.

W ostatnich kilkunastu latach Jego aktywność naukowa skupiała się na poznawaniu roli RNA w patogenezie chorób neurologicznych człowieka wywoływanych ekspansją sekwencji mikrosatelitarnych oraz na poszukiwaniu nowych metod eksperymentalnej terapii w tej grupie chorób. Badał również proces biogenezy cząsteczek mikroRNA, zaburzenia ich funkcji w chorobach mikrosatelitarnych oraz ulepszał narzędzia technologii interferencji RNA dla potrzeb terapii.

Do wcześniejszych osiągnięć naukowych profesora Krzyżosiaka należy opracowanie nowej metody badania struktury RNA w roztworze z wykorzystaniem właściwości jonów metali oraz rekonstytucja funkcjonalnego rybosomu z naturalnych białek i syntetycznego rRNA. Jego nowsze osiągnięcia to stworzenie strukturalnych podstaw do badań roli RNA w patogenezie chorób mikrosatelitarnych, stwierdzenie udziału toksycznego RNA w patomechanizmie choroby Huntintona i opracowanie nowego podejścia terapeutycznego dla tej choroby z wykorzystaniem cząsteczek siRNA działających jak mikroRNA.

Wyniki badań prowadzonych przez profesora Krzyżosiaka zostały trzykrotnie wyróżnione Nagrodą Polskiego Towarzystwa Biochemicznego im. Jakuba Parnasa za najlepszą pracę eksperymentalną wykonaną w polskim laboratorium. W roku 2004 został członkiem korespondentem PAN, w 2007 laureatem Nagrody FNP, a w 2013 odznaczony Krzyżem Oficerskim Orderu Odrodzenia Polski.

 

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Data publikacji: wtorek, 10. luty 2015 - 08:33; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:57; osoba wprowadzająca: Elżbieta Moroz

Rafał Zieliński (University of Texas, M.D. Anderson Cancer Center in Houston, USA)

Speaker: Rafał Zieliński, PhD (University of Texas, M.D. Anderson Cancer Center in Houston, USA)

Workshop: Grant writing

Time: Monday 15th July, Tuesday 16th July 2013

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Rafał Zieliński, biographical note

Dr. Rafal Zielinski holds a position at the Department of Experimental Therapeutics, University of Texas, MDAnderson Cancer Center in Houston, TX. He graduated from Catholic University of Lublin, Poland, where he also obtained his PhD. Dr. Zielinski received extensive postdoctoral training at National Institutes of Health, National Cancer Institute, Radiation Oncology Branch, Bethesda MD and Department of Experimental Therapeutics UT, MDAnderson Cancer Center where recently, he was promoted to Research Scientist. His scientific interest is focused on development of new therapies targeting HER2 and oncogenic transcription factors: STAT3, STAT5 and HIF-1a. Dr. Zielinski is an author and co-author of more than twenty peer-reviewed publications. As a Scientist in academic institution, Dr. Zielinski is actively involved in application for research support. His experience involves multiple application for federal (NIH, DOD, SPORE) as well as private foundation grants. Dr. Zielinski also served as reviewer of multiple scientific proposals.

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Data publikacji: piątek, 23. Styczeń 2015 - 14:14; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:06; osoba wprowadzająca: Elżbieta Moroz

Dan Tawfik (Weizmann Institute of Science in Rehovot, Israel)

Speaker: Prof. Dan Tawfik (Weizmann Institute of Science in Rehovot, Israel)

Talk: Laboratory molecular evolution

Time: Saturday 13th July 2013, 9:40

Talk: Protein strcuture-function in the light of molecular evolution

Time: Sunday 14th July 2013, 11:45

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lectures during Biotechnology Summer School


Dan Tawfik, biographical note

Born in Jerusalem, Prof. Tawfik received a B.Sc. in chemistry and biochemistry from the Hebrew University of Jerusalem in 1988, and an M.Sc. in biotechnology in1990. He did his doctoral work at the Weizmann Institute under the supervision of Profs. Zelig Eshhar and Michael Sela, and was granted a Ph.D. in 1995 on the basis of his thesis: “Towards Antibody-Mediated Peptide Hydrolysis.”

In 1996, Prof. Tawfik completed two years of postdoctoral research under Prof. Alan Fersht, at Cambridge University and the MRC Centre for Protein Engineering (UK). From 1997 to 2001, he held the position of senior research fellow at Sidney Sussex College, as well as at the MRC Centre for Protein Engineering, where he was appointed group leader in chemical biology in 1999. Prof. Tawfik joined the staff of the Department of Biological Chemistry at the Weizmann Institute of Science in thespring of 2001, where he serves now as full Professor. He has received numerous awards and fellowships, including the Sir Charles Clore Prize, the Weizmann Institute’s highest honor for a newly-appointed senior scientist, the Wolgin Prize, and the Haim Weizmann Prize by the City of Tel-Aviv, and the EMBO membership. He entered the field of protein evolution through his interest in enzyme engineering, when he realized that unraveling the mysteries of protein evolution is a charming intellectual endeavor and a powerful way of facilitating protein engineering. Research in the Tawfik laboratory integrates protein science, and chemical and evolutionary biology. Enzymes ranging from hydrolases to DNA methyltransferases are being studied, while addressing both the applicative and fundamental aspects of protein evolution. Proteins present a dichotomy. They are highly robust and remarkably proficient and specific. They can, nonetheless, rapidly change and adopt new structures and functions, as manifested in the rapid emergence of resistance in plants, insects, and bacteria, or of herbicide and pesticide degrading enzymes.

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Data publikacji: piątek, 23. Styczeń 2015 - 14:09; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:03; osoba wprowadzająca: Elżbieta Moroz

Juli Peretó (Valencia University, Spain)

Speaker: Prof. Juli Peretó (Valencia University, Spain)

Talk: Discussing on the origin of life as an educational tool in biochemistry

Time: Saturday 13th July 2013, 10:25

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Juli Peretó, biographical note

Juli Peretó is Tenured Professor at the Department of Biochemistry and Molecular Biology, and researcher at the Evolutionary Genetics Unit, Cavanilles Institute for Biodiversity and Evolutionary Biology, University of València. His research interests include the evolution of metabolism, the minimal genome concept, and the history of ideas on the natural origin and the artificial synthesis of life. He teaches metabolism in an evolutionary context to biologists, biochemists and biotechnologists. Currently coordinates a consortium of eight European universities in the Erasmus IP course Origin, Evolution and Future of the Biosphere. He was formerly Secretary of the International Society for the Study of the Origin of Life (ISSOL-The International Astrobiology Society) and has been elected as Second Vice President of ISSOL for the term 2011-2014. His most recent book, coauthored with A. Moya, is “Simbiosis: seres que evolucionan juntos” (Síntesis, Madrid, 2011).

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Data publikacji: piątek, 23. Styczeń 2015 - 14:06; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:04; osoba wprowadzająca: Elżbieta Moroz

Jarosław Marszałek (Intercollegiate Faculty of Biotechnology UG&MUG, Poland)

Speaker: Prof. Jarosław Marszałek (Intercollegiate Faculty of Biotechnology UG&MUG, Poland)

Talk: Evolution from Modern to Functional Synthesis

Time: Saturday 13th July 2013, 9:20

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Jarosław Marszałek, biographical note

Jaroslaw Marszalek is Tenured Professor at the Department of Molecular and Cellular Biology at Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk. He leads Laboratory of Evolutionary Biochemistry. The main focus of his research is the role of molecular chaperones of Hsp70 system in essential mitochondrial processes such as biogenesis of iron-sulfur clusters containing proteins and maintenance and propagation of mitochondrial genomes. He studies the role of Hsp70s in these processes from functional, structural and evolutionary perspective. He teaches Molecular Evolution. Prof. Marszalek is also a Visiting Associate Professor at the Department of Biochemistry, University of Wisconsin-Madison, USA.

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Data publikacji: piątek, 23. Styczeń 2015 - 13:50; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:05; osoba wprowadzająca: Elżbieta Moroz

Jean-Luc Lebrun

Speaker: Jean-Luc Lebrun, Writer and Trainer of Scientists in communication skills

Workshop: Grant writing

Time: Monday 15th July, Tuesday 16th July 2013

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Jean-Luc Lebrun, biographical note

Jean-Luc Lebrun has managed research programs while working at Apple Computer in its Advanced Technology Research group for over ten years. He subsequently invested his energy in the commercialization of research at Kent Ridge Digital Labs, a Singapore-based IT lab. He now leaves in San Jose California.

For the past twelve years, Jean-Luc Lebrun has been conducting courses on grant writing, scientific writing, and scientific presentation for more than three thousand scientists, researchers, clinicians, and doctoral students in South East Asia and Europe. He was recently in Krakow and Warsaw giving seminars on scientific writing for the Foundation for Polish Science. He willingly agreed to return to Poland, a country he appreciates, and share with the participants to the summer school of Biotechnology his practical knowledge on grant writing.

He is an author of three books on scientific writing and scientific presentations: "Scientific Writing 2.0 - a reader and writer's guide"; "When the scientist presents" (Both published by World Scientific Publishing Inc) and "Guide Pratique de rédaction scientifique"(published by EDP - éditions de Physique).

He is also co-designer of a computer program to assess the quality of a scientific paper prior to publication (SWAN - freely accessible online at http://cs.joensuu.fi/swan/). Team Members: Jean-Luc Lebrun, Tuomo Kakkonen, Tomi Kinnunen, Henri Leisma, Ernest Arendarenko.
SWAN is a Java application that takes a typical scientific paper (not a review paper) and analyses it to detect writing problems: lack of structure, lack of fluidity, lack of clarity, lack of focus (among others). It does so with the help of the writer who answers a few questions prior to automatic analysis. It delivers an extensive diagnostic report suggesting ways to improve the paper.

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Data publikacji: piątek, 23. Styczeń 2015 - 13:31; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:06; osoba wprowadzająca: Elżbieta Moroz

Grzegorz Kudla (MRC Human Genetics Unit, University of Edinburgh, Scotland)

Speaker: Grzegorz Kudla, PhD (MRC Human Genetics Unit, University of Edinburgh, Scotland)

Talk: Synonymous but not the same: causes and consequences of codon bias

Time: Sunday 14th July 2013, 10:15

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Grzegorz Kudla, biographical note

Grzegorz Kudla is a group leader at the MRC Human Genetics Unit, University of Edinburgh, Edinburgh, Scotland. After receiving his doctorate in the Maciej Zylicz lab, International Institute of Molecular and Cell Biology, Warsaw, Poland, he worked as a postdoc with Joshua Plotkin at Harvard University and with David Tollervey at the University of Edinburgh, to study the influence of codon bias on gene expression. He is currently developing experimental and bioinformatic tools to study regulation of gene expression, protein-RNA interactions, and RNA-RNA interactions. Since 2008 he has served as Academic Editor of the open access journal PLoS ONE.

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Data publikacji: piątek, 23. Styczeń 2015 - 13:27; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:06; osoba wprowadzająca: Elżbieta Moroz

Ryszard Korona (Jagiellonian University, Krakow, Poland)

Speaker: Prof. Ryszard Korona (Jagiellonian University, Krakow, Poland)

Talk: Evolution under failed selection

Time: Sunday 14th July 2013, 9:00

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Ryszard Korona, biographical note

Ryszard Korona is a professor at Jagiellonian University in Krakow. His PhD was on competitive behavior of beetles, post-doctoral training on co-evolution of bacteria-phage systems. For some fifteen years uses the budding yeast as an experimental organism in the study of evolutionary genetics and genomics. His research projects concentrate on: genetic determinants of major components of fitness, such as rate of growth and survival, stress resistance; spontaneous mutations, their rate of origin, selective value, dominance status, genetic interactions; molecular mechanisms of phenotypic buffering of mutational damage; experimental evolution of laboratory of microorganisms.

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Data publikacji: piątek, 23. Styczeń 2015 - 13:24; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:05; osoba wprowadzająca: Elżbieta Moroz

Angel Herráez (Alcalá University, Madrid, Spain)

Speaker: Prof. Angel Herráez (Alcalá University, Madrid, Spain)

Workshop: In Silico practical: "Molecular evolution illustrated using protein structure"

Time: Saturday 13th July 2013, 11:25

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24


Angel Herráez, biographical note

Angel Herráez holds a degree (BSc + MSc, 1985) in Chemistry from University of Valladolid, Spain. He followed his doctorate studies in the University of Alcalá, where he got the PhD degree in Biochemistry in 1990. He then spent one year as post-doc in the MRC Clinical Research Centre at Harrow, U.K. After that, he established back in the University of Alcalá as assistant professor, then associate professor, and finally (1997) in a tenured position as lecturer/associate professor in the Department of Biochemistry & Molecular Biology.

Angel Herráez’s research activity started on differentiation markers, with particular focus on membrane proteins. This evolved into studies of cell surface modification aimed at drug carrier systems and the process of blood cell removal from circulation as a possible target. His major research interest has been on structure of biomolecules and protein properties. Along time, he started to get involved in the development of materials to support teaching and learning, particularly in using the technological developments in computerised tools. He has developed some expertise in bioinformatics, mainly on (bio)molecular structure visualisation. While maintaining a collaboration with colleagues in the field of mechanisms of action of antitumour agents, his interest and dedication has been increasingly devoted to the facilitation of learning and the development of interactive resources for both instructors and students. He is also collaborating with a research group at Universidad Complutense in Madrid who works on nutritional epidemiology and health promotion.

Fruit of his activity in the field of education, Angel Herráez has developed a website, http://biomodel.uah.es, where he builds all his materials and offers them openly and free to the community. Since the year 2000, he is member of a joint effort to share educational materials in Spanish, BioROM, which has been publishing a CD-ROM nearly every year between 2001 and 2010 and stays available and updated in the website www.biorom.uma.es and a few mirror sites.

On 2001 Angel Herráez, together with Prof. José Luque, published a book in Spanish on Molecular Biology and Genetic Engineering (Harcourt/Elsevier, ISBN 978-84-8174505-4) which has been successfully accepted both as a textbook and as a reference for professionals in diverse areas where the molecular concepts and techniques are increasingly needed. The second edition of this book, now authored only by Angel, was released in 2012 (Elsevier, ISBN 978-84-8086-647-7).

Since January 2007 Angel Herráez is a member of the Editorial Board of the Journal Biochemistry and Molecular Biology Education. In the period 2008-2012 he acted as coordinator of the Education Group of the Spanish Society of Biochemistry and Molecular Biology (SEBBM). As such, he led some workshops and courses associated to the yearly congresses of SEBBM. Among them, he organised the “2010 Workshop on Biochemistry Education: Assessment Strategies in Protein Structure”, an IUBMB-sponsored Educational Activity with an international audience. He was also in the Organising Committee of the 22nd IUBMB / 37th FEBS Congress (Sevilla, 2012) responsible for coordinating the educational activities during the congress together with IUBMB and FEBS Education Committees.

Angel is a member of the Education Committee of FEBS since January 2012.

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Data publikacji: piątek, 23. Styczeń 2015 - 13:13; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:04; osoba wprowadzająca: Elżbieta Moroz

Wiesław Babik (Jagiellonian University, Krakow, Poland)

Speaker: Prof. Wiesław Babik (Jagiellonian University, Krakow, Poland)

Talk: History of divergence and gene flow in hybridizing newts

Time: Sunday 14th July 2013, 13:45

Venue: Biotechnology Summer School 2013, Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited lecture during Biotechnology Summer School


Wiesław Babik, biographical note

Wiesław Babik is an associate professor at the Jagiellonian University in Kraków. He received his PhD in 2004, and worked as a postdoc in the Helmholtz Centre for Environmental Research in Halle (Germany) and the Imperial College of London. He uses information from contemporary DNA sequences to infer history of populations. In particular he is interested in the causes, demography and the age of intraspecific differentiation, as well as in studying the extent of gene flow between diverging populations. He also studies variation of the Major Histocompatibility Complex (MHC) genes in natural populations, with special emphasis on the effects of natural selection and genetic drift on the patterns of variation at the molecular level. He is an associate editor of the Proceedings of the Royal Society B: Biological Sciences.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:44; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:05; osoba wprowadzająca: Elżbieta Moroz

Tomasz Besta (University of Gdansk, Poland)

Speaker: Prof. Tomasz Besta (University of Gdansk, Poland)

Talk: Public Understanding of Biotechnology

Time: Friday, 5th of September 2014, 8:30 (gr. A), 10:45 (gr. B)

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Tomasz Besta, biographical note

Social psychologist and an associate professor at the University of Gdansk, Institute of Psychology. He obtained his PhD in 2010 from the Polish Academy of Science and since then has been involved as a principal investigator or main researcher in national and international research projects (granted by, for example, the Polish National Science Center, the European Commission Jean Monet Programme and Norway Grants in the Polish-Norwegian Research Programme). His main research area is social and personality psychology; he analyzes the mechanisms of intergroup relations, dynamics of social identities, and the consequences of the need for certainty and predictability. Recently, he has been involved in research into public understanding of technology and human cognitive distortions related to the protection of world-views and beliefs. He is also an ad-hoc reviewer in national and international journals and one of the editors of the Current Issues in Personality Psychology.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:33; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:01; osoba wprowadzająca: Elżbieta Moroz

Barbara Kijewska (University of Gdansk, Poland)

Speaker: Prof. Barbara Kijewska (University of Gdansk, Poland)

Talk: Public Understanding of Biotechnology

Time: Friday, 5th of September 2014, 8:30 (gr. A), 10:45 (gr. B)

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Barbara Kijewska, biographical note

Political scientist and an associate professor at the Institute of Political Science at the University of Gdansk. She has been involved as a co-investigator in national and international research projects including the Jean Monet Programme (the European Commission), a strategic research project of the National Centre for Research and Development (NCBR) “Technologies supporting the development of safe nuclear energy”, “Public Understanding of Technology” (University of Gdansk). In particular, she is interested in studies regarding the understanding of technologies and mass media coverage of science and technology.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:30; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:02; osoba wprowadzająca: Elżbieta Moroz

Sylwia Mrozowska (University of Gdansk, Poland)

Speaker: Prof. Sylwia Mrozowska (University of Gdansk, Poland)

Talk: Public Understanding of Biotechnology

Time: Friday, 5th of September 2014, 8:30 (gr. A), 10:45 (gr. B)

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Sylwia Mrozowska, biographical note

Associate professor at the Institute of Political Science at the University of Gdansk and the head of the post-graduate studies in the field of “Civic activation of local communities in the European Union”. She is the principal investigator and coordinator of national and international projects (the National Center for Research and Development (NCBR), the Jean Monnet Programme, the Swiss-Polish Cooperation Programme, the Ministry of Labour and Social Policy) and the author of publications dealing with the issues of lobbing, strategies, democratic engagement, social participation, civic society, public understanding of technology. Currently, her work focuses on the development of the social communication model in the scope of new nuclear technologies (strategic research project NCBR).

In 2013 Sylwia Mrozowska became a founding member of the Polish Society of Technology Assessment.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:27; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:02; osoba wprowadzająca: Elżbieta Moroz

Konrad Ocalewicz (University of Gdansk, Poland)

Speaker: Prof. Konrad Ocalewicz (University of Gdansk, Poland)

Talk: Fish as model organisms in biomedical research

Time: Thursday, 4th of September 2014, 8:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Konrad Ocalewicz, biographical note

Konrad Ocalewicz received his M.Sc.in the field of biotechnology in animal breeding from University of Agriculture and Technology in Olsztyn in 1998 and his PhD in agriculture and fisheries from University of Warmia and Mazury in 2002. In 2005, Konrad Ocalewicz completed two years of postodoctoral research in Laboratoire de Genetique des Poissons, INRA, Jouy-en-Josas, France where he studied functionality of L-gulono-gamma-lactone oxidase gene in fish. HeIn 2006 he was also involved in the international project Control of sex in Atlantic halibut: Towards production of monosex all-female stocks conducted in The University of Nordland (Bodo, Norway) and University in Stirling (UK) (2006). His scientific interests cover a range of issues such as genetic sex determination and evolution of the vertebrate sex chromosomes, development of the isogenic and clonal fish lines, recovery of the fish gene pools through artificially induced androgenesis, genomic organization of the telomeric DNA sequences and role of the telomerase in healing of the radiation-induced Double Strand Breaks. Results of his research on the spontaneous and induced chromosome mutations in the rainbow trout were part of his  D.Sc. dissertation defended at the Department of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn in 2011. Since 2013, Konrad Ocalewicz has been an assistant professor at the Department of Marine Biology and Ecology, Institute of Oceanography, University of Gdańsk. He also serves as an Assistant Editor in the Journal of Fish Biology, the official journal of The Fisheries Society of the British Isles (FSBI).

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Data publikacji: piątek, 23. Styczeń 2015 - 12:21; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:00; osoba wprowadzająca: Elżbieta Moroz

Małgorzata Wiweger (International Institute of Molecular and Cell Biology, Poland)

Speaker: Małgorzata Wiweger, PhD (International Institute of Molecular and Cell Biology, Poland)

Talk: Zebrafish husbandry and health

Time: Thursday, 4th of September 2014 11:15

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Małgorzata Wiweger, biographical note

Head of the Zebrafish Core Facility at the International Institute of Molecular and Cell Biology in Warsaw, Poland. She graduated at the Warsaw University of Life Sciences in Poland and obtained PhD at the Swedish University of Agricultural Sciences in Uppsala, Sweden in the field of plant development. In 2004 she switched from plants to animal model (zebrafish) and since then worked as a post-doctoral fellow at the University of Sheffield (UK), Leiden University Medical Centre, Leiden University and ZF-screens in Leiden, The Netherlands. She is interested in proteoglycans regulating embryo development and uses zebrafish as a model for studies on the skeletal development in normal and pathological conditions. Her latest projects focused on skeletal tuberculosis and non-classical aspects of multiple osteochondromas.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:14; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:59; osoba wprowadzająca: Elżbieta Moroz

Cecilia Lanny Winata (International Institute of Molecular and Cell Biology, Poland)

Speaker: Cecilia Lanny Winata, PhD (International Institute of Molecular and Cell Biology, Poland)

Talk: Zebrafish in the study of developmental genomics

Time: Thursday, 4th of September 2014, 12:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Cecilia Lanny Winata, biographical note

Group leader at the International Institute of Molecular and Cell Biology, Warsaw.
Research interest: developmental biology using zebrafish as a model organism, the study of developmental mechanisms using genomics.
She obtained her PhD in 2009 from the National University of Singapore in the field of zebrafish developmental biology. She worked as a post doctoral fellow at the Genome Institute of Singapore where she picked up genomics techniques and applied them to study the regulation of maternal to zygotic transition and functional characterization of a transcription factor in zebrafish.  Currently, her lab is studying transcriptional regulation and epigenetics during heart development, as well as the regulation of early embryonic development in zebrafish.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:12; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:59; osoba wprowadzająca: Elżbieta Moroz

Klaus Schughart (Helmholtz Centre for Infection Research, Germany)

Speaker: Prof. Klaus Schughart (Helmholtz Centre for Infection Research, Germany)

Talk: Host-pathogen-interactions during influenza infections – studies in the mouse model system

Time: Wednesday, 3rd of September 2014, 15:45

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Klaus Schughart, biographical note

Klaus Schughart is Head of the Department of Infection Genetics (INFG) at the Helmholtz Center for Infection Research (HZI) in Germany. The HZI is a government funded public research institute dedicated to perform basic research on host-pathogen interactions with the aim to develop new strategies for diagnostics, prevention and therapy of infectious diseases.

The main research interest in the IFNG department is to understand the role of genetic factors that determine resistance or susceptibility to influenza A virus infections. For these studies, we are using the mouse as model system. We established models for lethal and non-lethal infections using different mouse populations and knock-out models.

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Data publikacji: piątek, 23. Styczeń 2015 - 12:06; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:58; osoba wprowadzająca: Elżbieta Moroz

Amy Sater (University of Houston, USA)

Speaker: Prof. Amy Sater (University of Houston, USA)

Talk: Xenopus: a Model System for Studies of Gene Regulation and Vertebrate Development

Time: Friday, 5th of September 2014, 15:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Amy Sater, biographical note

Developmental biologist and Professor of Biology and Biochemistry, University of Houston.

She obtained her Ph.D. from the University of Texas before embarking upon postdoctoral work at the University of California at Berkeley. Her ongoing research interests include cell signaling and the molecular regulation of embryonic development in the African Clawed Frog Xenopus laevis.  She has also been extensively involved in the development of genomics resources in Xenopus, contributing to genetic mapping and genome assembly in Xenopus tropicalis; she also served on the Xenopus Genome Steering Committee 2005-2013.  Her current studies address the roles of microRNAs in the initiation of neural development, using a combination of genetic and biochemical approaches.  She served as Instructor for the “Cell and Developmental Biology of Xenopus” course at Cold Spring Harbor Laboratory from 2011-2014.

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Data publikacji: piątek, 23. Styczeń 2015 - 11:54; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:58; osoba wprowadzająca: Elżbieta Moroz

Jan Sadowski (Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Poland)

Speaker: Prof. Jan Sadowski (Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Poland)

Talk: Arabidopsis – The Model Plant For Biotechnology

Time: Friday, 5th of September 2014, 14:15

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Jan Sadowski, biographical note

Head of Biotechnology Department at Faculty of Biology, Adam Mickiewicz University (from 2001 up to now). He received extensive doctoral and postdoctoral training in plant molecular genetics and genomics: Fullbright-Hays fellowship, 1979-1980 (12 months); Rutgers University (4 months) and Texas A&M University (8 months); post-doc at University of Perpignan, France (18 months in the period of 1987-1992); geneticist position at University of California, Davis, USA (2.5 years, 1993-1996). His main achievements  are connected with understanding the structure, organization and evolution of Brassicaceae genomes. Currently, he is involved in genome-wide functional studies on cellular signalisation networks activated in plant cells in response to environmental stresses, such as drought, salinity and ozone. His team applies diverse physiological and genetic tests including specific signalisation pathway inhibition or activation and agro-transformation with protein kinases (CDPK and MAP kinases) and protein phosphatases (PP2C ABI1 and ABI2) encoding genes, combined with the genetic analysis of insertional mutants and/or specific transient gene expression. Selected genes with beneficiary characteristics for plant adaptation to drought stress (such as BnCDPK5 and AtCDPK5) or other interesting phenotypes (BnABI1 and AtABI) have been introduced to the winter rapeseed to prove and study further their application values. Prof. Sadowski is an author and co-author of dozens of peer-reviewed publications (Genetics, Nucleic Acids Research, Plant Journal, Journal of Experimental Botany, Molecular Plant, Molecular and General Genomics, among others).

 

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Data publikacji: piątek, 23. Styczeń 2015 - 11:44; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:00; osoba wprowadzająca: Elżbieta Moroz

Jolanta Paradziej-Łukowicz (Medical University of Gdansk, Poland)

Speaker: Jolanta Paradziej-Łukowicz, PhD (Medical University of Gdansk, Poland)

Talk: Ethical and legal rules and regulations for animals experiment performance

Time: Wednesday, 3rd of September 2014, 11:45

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Jolanta Paradziej-Łukowicz, biographical note

Director of Tri-City Central Animal Laboratory – Research and Service Centre of the Medical University of Gdansk.

She received MSc and PhD at the Faculty of Pharmacy, the Medical University of Gdańsk, and further scientific training at the Department of Pharmaceutical Technology and at the Biochemistry Chemical Faculty, Technical University of Gdansk.

She was particularly involved in many projects associated with investigation of potential anticancer drugs anticancer activity on murine tumors and human tumor xenograft models in vivo. She also cooperates with biochemical and pharmaceutical industry in the field of potential antidiabetes drugs activity investigating.

In general she has expertise in conducting animal experiments and evaluation biological activity of compounds of chemical and natural origin. In 2011 -2013 she took part in Expert Working Group (EWG) on Education and Training within the context of 2010/63/EU Directive. For the past three year she also has organizing seminars and practical trainings for people performing experiments or doing work with or around laboratory animals with regional and state-wide range.

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Data publikacji: piątek, 23. Styczeń 2015 - 11:26; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:01; osoba wprowadzająca: Elżbieta Moroz

Maria Mione (Karlsruhe Institute of Technology, Germany)

Speaker: Prof. Maria Mione (Karlsruhe Institute of Technology, Germany)

Talk: The zebrafish as a tool in cancer genetics and cancer cell biology

Time: Thursday, 4th of September 2014, 9:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Maria Mione, biographical note

Group Leader at the Institute of Toxicology and Genetics Karlsruhe Institute of Technology, KIT.

Research interest: Cancer and disease models using the zebrafish platform. Special focus on genetic and epigenetic mechanisms of transformation and cell reprogramming by oncogenes.

Dr Mione graduated in Medicine and Surgery at the University of Rome “La Sapienza”, trained as a neurologist and received a PhD in Neurobiology from University College London. After postdoctoral work at University of California at San Francisco, on her return to U.K, she adopted the zebrafish for her studies on neural development and disease. In 2005 she moved to the Institute of Molecular Oncology in Milan and developed zebrafish models for the study of cancer cell biology. Dr. Mione’s work focuses on understanding early events in melanoma, myeloid leukemia and glioma development, including cancer initiating cells, mechanisms of transformation, epigenetic regulation and immune responses. From 2012, she is Visiting Professor at the Institute of Toxicology and Genetics at Karlsruhe Institute of Technology (KIT). She is an active member of the international community of zebrafish researchers. She organized of the VI European Development and Genetics Zebrafish meeting, held in Rome in 2009, and the satellite workshop on Cancer and Immune Responses in Zebrafish in July 2009. She was part of the planning committee of the 4th Strategic Conference of Zebrafish Investigators in Asilomar, 2009-2011, Vice Chair of the Cost action BM8024, EuFishBioMed and funding member of the European Zebrafish & Medaka Society (http://www.eufishbiomed.kit.edu/). She is a member of the scientific board of the newly established Zebrafish Disease Models society

(http://www.zdmsociety.org/internation_expert_board.html).

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Data publikacji: piątek, 23. Styczeń 2015 - 11:17; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:59; osoba wprowadzająca: Elżbieta Moroz

Magdalena Mikołajczyk-Chmiela (University of Łódź, Poland)

Speaker: Prof. Magdalena Mikołajczyk-Chmiela (University of Łódź, Poland)

Talk: Guinea pig model of Helicobacter pylori infection, inflammation and immune response

Time: Wednesday, 3rd of September 2014, 12:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Magdalena Mikołajczyk-Chmiela, biographical note

With a master degree on biology, microbiology as speciality, upon her PhD on Immunology in 1991 and habilitation in 1999, Magdalena Mikołajczyk-Chmiela was nominated in 2005 on the position of permanent Professor (medical microbiology, immunology) at the Faculty of Biology and Environmental Protection, University of Lodz.  She is currently head of the Department of Immunology and Infectious Biology at the Institute of Microbiology, Biotechnology and Immunology. Her research concerns the immunology of infectious diseases including: immune processes regulating host-pathogen interactions, bacterial virulence factors that determine the course of infections, the use of microorganisms in the design and manufacture of biological components for potential therapeutic use, prevention and diagnostic. With particular attention she leads research on Helicobacter pylori infections, which are responsible for gastric and duodenal ulcers and even stomach cancers. Work on this subject she began in 1992, being a member of the research team at the Department of Medical Microbiology, Lund University in Sweden. With her experience she published numerous papers, review articles, coordinated and participated in a number of research projects supported by the Polish Research Committee, the Polish Ministry of Science and Education as well as the National Center of Science, and evaluated them as an expert. She is a member of the Scientific Council of the Institute of Medical Biology, Polish Academy of Sciences and the editorial board of the World Journal of Gastroenterology. She shares her professional activity between research work and academic professor activity.

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Data publikacji: piątek, 23. Styczeń 2015 - 11:06; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:59; osoba wprowadzająca: Elżbieta Moroz

Aleksandra Małyska (Institute of Bioorganic Chemistry of Polish Academy of Sciences, Poland)

Speaker: Aleksandra Małyska (Institute of  Bioorganic Chemistry of Polish Academy of Sciences, Poland)

Talk: Are we ready for GMO?

Time: Saturday, 6th of September 2014, 8:30

Workshop: GMO and GM goods on Polish market, Factors underlying  commercialization of  GMO in Poland within EU

Time: Saturday, 6th of September 2014, 10:15

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lectures during Biotechnology Summer School


Aleksandra Małyska, biographical note

Aleksandra Małyska received a Master’s degree in medical biotechnology at Poznan University of Medical Sciences in 2010. The second area of her research involves social sciences. She carried out a Directed Individual Study in social sciences and received a Master’s degree in Psychology at Adam Mickiewicz University in Poznan in 2013. She continues her research within PhD studies at Lodz University of Technology. Since 2013 she works at Institute of Bioorganic Chemistry, Polish Academy of Sciences. Her research focuses on: public perception of innovative biotechnology, prospects for the commercial use of genetically engineered products, and biotechnology within the knowledge based bio-economy (KBBE).

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Data publikacji: piątek, 23. Styczeń 2015 - 11:00; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:00; osoba wprowadzająca: Elżbieta Moroz

Alessio Mengoni (University of Florence, Italy)

Speaker: Prof. Alessio Mengoni (University of Florence, Italy)

Topic: Principles of genome analysis and comparative bacterial genomics

Time: 7-14 January, 2015

Venue: Intercollegiate Faculty of Biotechnology, Kładki 24

Category: Invited Lectures

Lectures for students - more information here [link]. Please check PROGRAM [PDF].


Alessio Mengoni, biographical note

Assistant Professor (Reader) in the School of Science, class of Genomics, Master Degree course in Molecular Biotechnologies.

I'm working on the molecular microbial ecology and bacterial genomics of the nitrogen fixing symbiotic bacterium Sinorhizobium meliloti and of bacterial communities associated with plants.

 

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Data publikacji: piątek, 23. Styczeń 2015 - 10:37; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:56; osoba wprowadzająca: Elżbieta Moroz

Philip C Lyons (University of Houston-Downtown, USA)

Speaker: Prof. Philip C Lyons (University of Houston-Downtown, USA)

Talk: Diversity in the composition and function of fungal communities of native and farmed prairie soils

Time: Friday, 5th of September 2014, 16:45

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Philip C Lyons, biographical note

Phil Lyons earned his PhD in Plant Pathology from the University of Georgia and MS in Plant Pathology from Texas A & M University.  He was Post-doctoral Associate in the Departments of Plant Pathology and Biology at Purdue University, and is now Associate Professor of Biology and Microbiology in the Department of Natural Sciences at UHD where he teaches courses on Biology of Fungi, Plant Biology, Microbial Biotechnology, and on Methods in Molecular Biology and Biochemistry.  He also teaches General and Introductory Biology for science majors and non-majors.  Lyons’ current research concerns diversity and ecology of tallgrass prairie soil fungi, including effects of farming and restoration.  A related project involves the occurrence and variation in substrate specificities of laccases and other oxidoreductases produced by prairie soil fungi.  He recently began a project on the diversity and geographical distribution of truffles (Tuber spp.) associated with pecans (Carya illinoiensis) and other hardwoods throughout different vegetation zones of Texas (USA)  Prior research involved plant-fungal interactions, including both pathogenic relationships in corn and sorghum and endophytic symbioses in tall fescue grass.

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Data publikacji: piątek, 23. Styczeń 2015 - 10:29; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:58; osoba wprowadzająca: Elżbieta Moroz

Scott Gold (University of Georgia, USA)

Speaker: Prof. Scott Gold (University of Georgia, USA)

Talk: An earful of corn smut

Time: Wednesday, 3rd of September 2014, 8:30

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Scott Gold, biographical note

Research Plant Pathologist for the U.S. Department of Agriculture - Agricultural Research Service.  Gold earned a PhD in Plant Pathology from the University of California in the laboratory of the pioneer plant pathologist Noel Keen.  He joined ARS in 2011 after 17 years as a Professor of Plant Pathology at the University of Georgia (UGA). At UGA among other fungal plant pathogens Gold explored the genetics of dimorphism in the corn smut pathogen, Ustilago maydis.  He and colleagues, primarily through forward genetic approaches, demonstrated the control of fungal dimorphism (budding vs filamentous growth forms) by the cAMP and MAP kinase signaling pathways. This ability to convert between these forms is critical to the ability of the pathogen to cause disease.  Currently at the USDA-ARS, Gold is involved in studies toward the control of food contamination by poisonous mycotoxins. Gold has been an active volunteer in the American Phytopathological Society (APS) serving as a two term member of the APS Public Policy Board with focus on microbial genomics and culture collections.  He is the recipient of the APS 2006 Outstanding Volunteer award and the 2010 APS Excellence in Teaching Award .  He just completed a three year term as the inaugural Director of the APS Office of Education. While carrying out ARS research he continues to teach a general science elective course on that amazing biology of fungi at UGA entitled "Fungi, friends and foes".

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Data publikacji: piątek, 23. Styczeń 2015 - 10:14; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:57; osoba wprowadzająca: Elżbieta Moroz

Michael Bölker (Philipps University of Marburg, Germany)

Speaker: Prof. Michael Bölker (Philipps University of Marburg, Germany)

Talk: Of fungi and men: Ustilago maydis as a model system to study ribosomal readthrough and peroxisome function

Time: Wednesday, 3rd of September 2014, 9:45

Venue: Biotechnology Summer School 2014, OW Syrenka, Stegna

Category: Invited lecture during Biotechnology Summer School


Michael Bölker, biographical note

Professor for Genetics at the Department of Biology, Philipps University Marburg. He obtained his PhD in biochemistry at the Institute for Genbiological Research in Berlin working on the field of bacteriophage genetics. Post doctoral fellow at the Institute for Microbiology and Genetics of the Ludwig-Maximilians University Munich working on fungal mating type determination. Since 1997 full professor in Marburg. Research interests: Regulation of morphogenesis and cytokinesis in the dimorphic fungus Ustilago maydis. Functional genomics to study peroxisome function and fungal secondary metabolism. Translational recoding and its function for intracellular localization of proteins. Michael Bölker is member of the Marburg Center for Synthetic Microbiology (SYNMIKRO) and the Frankfurt Excellence Cluster for Integrative Fungal Research.

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Data publikacji: piątek, 23. Styczeń 2015 - 09:30; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:57; osoba wprowadzająca: Elżbieta Moroz

Michał Dąbrowski (Nencki Institute, Poland)

Speaker: Michał Dąbrowski, PhD (Nencki Institute, Poland)

Talk: Analysis of global transcriptional regulation in brain starting from genomic and expression data

Time: April 11, 2014, 9:00

Venue: Intercollegiate Faculty of Biotechnology of UG&MUG, Kładki 24, Gdańsk, lecture hall B

Category: Invited seminar


Michał Dabrowski, biographical note

Physician by education, PhD in experimental molecular biology, about 10 years’ experience in bioinformatics, mainly analysis of global gene expression and regulatory genomics data.
Employment history (main places): Nencki Institute, Szpital Specjalistyczny w Kościerzynie, Katholieke Universiteit Leuven. Currently: Nencki Institute, Laboratory of Molecular Neurobiology, head: prof. Bożena Kamińska.
Key scientific achievements: demonstration of cell-autonomous regulation of differentiation of hippocampal neurons, identification of transcriptional regulators common to stroke and seizures, demonstration that matrix attachment region binding protein modulates transcriptional activation, identification of key proteins stimulating host microglia to promote tumor growth, creation of the first regulatory genomics database for the rat.
Ongoing projects: a bioinformatics project of creation of a portal with tools for regulatory genomics, and a (starting) experimental project utilizing very high-throughput next generation sequencing to identify TFs involved in microglia reeducation by glioma.

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Data publikacji: piątek, 23. Styczeń 2015 - 08:10; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:03; osoba wprowadzająca: Elżbieta Moroz

Vladimir Teif (German Cancer Research Center, Heidelberg)

Speaker: Vladimir Teif, PhD (German Cancer Research Center DKFZ and BioQuant, Heidelberg)

Talk: Deciphering the rules of epigenetic regulation during stem cell development

Time:  June 27, 2014, 10:00

Venue: Intercollegiate Faculty of Biotechnology of UG&MUG, Kładki 24, Gdańsk, lecture hall B

Category: Invited seminar

See abstract [PDF]

 

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Data publikacji: czwartek, 22. Styczeń 2015 - 14:51; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 12:02; osoba wprowadzająca: Elżbieta Moroz

Binay Chaubey (Intercollegiate Faculty of Biotechnology UG&MUG, Poland)

Speaker: Binay Chaubey, PhD (Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Poland)

Talk: Intervention of HIV replication using anti-sense approach

Time: October 31, 2014, 9:00

Venue: Intercollegiate Faculty of Biotechnology of UG&MUG, Kładki 24, Gdańsk, Lecture Hall B

Category: Lecture

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Data publikacji: poniedziałek, 22. Grudzień 2014 - 11:44; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:56; osoba wprowadzająca: Elżbieta Moroz

Jose Maria Valpuesta (Centro Nacional de Biotecnología, Spain)

Speaker: Jose Maria Valpuesta, PhD (Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Spain)

Talk: The protein folding pathway: a coordinated network of molecular machines

Time: October 17, 2014, 9:00

Venue: Intercollegiate Faculty of Biotechnology of UG&MUG, Kładki 24, Gdańsk, Lecture Hall B

Category: Invited seminar


José María Valpuesta, biographical note

José María Valpuesta obtained his Ph.D. degree in biochemistry at the University of the Basque Country, Spain in 1985. Later he worked at the Centro de Biología Molecular (CSIC/Madrid, Spain). In 2003 he obtained the professor tile and started working at the Centro Nacional de Biotecnología. In 2006-7 held position of Vice-director and 2007-13 director of Centro Nacional de Biotecnología, one of the most important centers of molecular biology in Spain. Between 2005 and 2009 prof. Valpuesta held position of President of the Spanish Microscopy Society. Currently he is head of the Macromolecular Structure Department of the National Centre of Biotechnology.

As the researcher prof. Valpuesta is co-author of 137 indexed papers (among others in Nature, Science, Nat Struct. Mol. Biol., Nat Cell Biol, Mol. Cell, PNAS USA, EMBO J.), in the field of membrane structure, protein folding, molecular chaperones, macromolecular complexes and electron microscopy. Citation Hirsch index: 42 (~5700 citations). Author of 1 book and 5 chapters in collective books. His achievements were honored by awards granted by Spanish Ministry of Education, Bruker Prize of the Biophysical Spanish Society, European Microscopy Society. In addition, prof. Valpuesta is the member of “Faculty of 1000” and “Academia Europaea”. He worked as reviewer for National Science Foundation (USA), Israel Science Foundation, Human Frontiers Science Foundation, Cancer Research UK, Wellcome Trust Foundation, Cancer Research UK, Argentinian Science Foundation (FONDECIT) and several Spanish Funding agencies.

Prof. Valpuesta as teacher gives lectures about Biomedicine, Molecular and Cell Biology and Biophysics at Universidad Autónoma de Madrid. Moreover, occasionally he gives lectures at University of Crete (Greece), Lisbon and Porto (Portugal), Santiago (Chile). Until 1995 he was supervisor of 10 postdocks, 15 Ph.D students and 6 Master students.

During last 10 years prof. Valpuesta has helped to establish cryoelectron microscopy at the Centro Nacional de Biotecnología (CNB), and have contributed to forming a core of seven groups at the institute that use this and other techniques, complemented by image processing tools, to structurally characterize a large variety of biological specimens. This community of electron microscopists is perhaps unique in the world and certainly in Spain, where his group is a reference. The most influential part of his work deals with the structural and functional characterization of various chaperones, which has helped to structurally confirm the existence of a network of interactions between different chaperones that make the protein folding pathway more efficient. He has published more than 60 papers over the last 10 years, some in such journals as Science, Mol. Cell, Nat Cell Biol, Nat Struct Mol Biol, J Exp Med, PNAS USA, and EMBO J. Seven of these papers were selected by the “Faculty of 1000”; his work has received more than 2500 citations since 2009.

He also pioneered in Spain the use of single-molecule techniques such as optical tweezers, which have been used to study the forces involved in the function of different protein and nucleic acid molecules.

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Data publikacji: poniedziałek, 22. Grudzień 2014 - 11:37; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:56; osoba wprowadzająca: Elżbieta Moroz

Agnieszka Bernat-Wójtowska (Intercollegiate Faculty of Biotechnology UG&MUG, Poland)

Speaker: Agnieszka Bernat-Wójtowska, PhD (Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Poland)

Talk: Embryonic stem cells: tools, cure and more

Time: November 28, 2014, 9:00

Venue: Intercollegiate Faculty of Biotechnology of UG&MUG, Kładki 24, Gdańsk, lecture hall B

Category: Lecture

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Data publikacji: poniedziałek, 22. Grudzień 2014 - 09:54; osoba wprowadzająca: Elżbieta Moroz Ostatnia zmiana: wtorek, 28. Listopad 2017 - 11:56; osoba wprowadzająca: Elżbieta Moroz