Retron Eco2: Of DNA making and RNA breaking in bacterial immunity
Speaker: dr Patrick Pausch, Vilnius University - Life Sciences Center, Lithuania
Talk: Retron Eco2: Of DNA making and RNA breaking in bacterial immunity
Time: 21.11.2025
Venue: Intercollegiate Faculty of Biotechnology, Abrahama 58, hall 042B

Dr Patrick Pausch is a biochemist and structural biologist whose research group explores the diversity, mechanisms, and applications of bacterial immune systems. Before establishing his laboratory in Vilnius in 2021, Patrick was a postdoctoral scholar with Jennifer Doudna at UC Berkeley, where he developed a hypercompact CRISPR nuclease. His team now studies novel CRISPR systems, molecular mechanisms of phage–host interactions, and newly discovered bacterial immune pathways. In his seminar, he will focus on one of these systems, which produces single-stranded DNA and degrades RNA to provide bacteria with immunity against phages.