Neoantigen discovery & proteomics development at International Centre for Cancer Vaccine Science

Speaker: Dr Sachin Kote

Talk: "Neoantigen discovery & proteomics development at International Centre for Cancer Vaccine Science"

Time: 11.06.2021, 9:00 am

Venue: Online in the "IFB seminars" group of MsTeams. Group password: ypidr3d.

I am acting team leader of the chemical biology group at the International Centre for Cancer Vaccine Science (ICCVS). I am currently leading the neoantigen discovery/immunopeptidomics projects and proteomics development at ICCVS, University of Gdansk, Poland (www.iccvs.ug.edu.pl) since 2018.

I have specialized in peptidomics, proteomics, and cancer vaccine science. I have been working in the field of proteomics concerning health, environment, and safety for the past 12 years. I started my research career as a research project assistant in the proteomics laboratory at the National Chemical Laboratory (NCL), India. Herein, I have developed a strong interest in proteomics, mass spectrometry (MS), and biomarker discovery. Afterward, I moved to Italy for doctoral studies focusing on invitro and invivo nano-bio-interactions, biomarker findings upon nano-exposure, and nanotoxicology using advanced proteomics tools. I have completed my doctoral studies with an excellent Ph.D. award from the University of Salento, Lecce, Italy. Later on, I moved to north Italy for my first postdoctoral studies at the Istituto Italiano di Tecnologia (IIT), Genova, Italy. During my tenure, I developed biological/protein nanoparticles for the safe delivery of nanomedicine applications. In the second but very challenging project, I have developed a dissolution test for risk assessment nanomaterials. I am proud to say that our development of dissolution test is included in the nano-regulatory guidelines i.e., The Organization for Economic Co-operation and Development (OECD, ENV/JM/MONO, 2020, 9) guidelines. These guidelines are applicable in 36 industrialized countries in North and South America, Europe, Asia, and the Pacific.

Additionally, I have a background in Bioinformatics, Clinical Research & Clinical Data Management (CRCDM), and Diploma in Medical Laboratory Technology (DMLT).